166 NEW YORK ZOOLOGICAL SOCIETY: 
tion of the Marchii method show no degenerated fibers either in 
the columns of the cord or in the surrounding nerve trunks. 
Dorsal Cord.—The same changes noted in the cervical cord 
are also present in the dorsal segments. A few of the ganglion 
cells show, however, an abnormal brownish pigmentation. No 
degenerated fibers are demonstrable by the Busch method. 
Lumbar and Sacral Cords.—-Changes similar to those described 
above are present. The entire spinal cord as represented by 
these sections may be said to be practically normal. 
Spleen.—The blood vessels are markedly congested through- 
out and there is a general extravasation of red blood cells through 
the splenic pulp. The Malpighian bodies show many evidences 
of acute lymphoid hyperplasia. Extensive areas of pigmentation 
are present in places, apparently resulting from the breaking 
down of many red blood cells. 
Bone.—Shaft of femur—vVhe fatty tissue of the marrow 1s 
largely replaced by dense masses of mononuclear and polynuclear 
leucocytes, fibroblastic and plasma cells, among which are found 
frequent multinuclear and mononuclear giant cells. Evidences 
of karyokinetic division are frequent among these cells, but in 
places fibroblastic cells predominate and a mucoid-like tissue 1s 
found replacing the marrow. Osteoclasts are found abundantly 
at the juncture with the compact tissue and these cells have largely 
replaced the endostium and, in places, are evidently causing active 
resorption of the osseous tissue. Some of the larger Haversian 
canals in the compact bone are surrounded by osteoid tissue from 
which the lime salts have evidently been removed leaving the 
general structure very similar to that of normal bone with the 
exception that the bone cells have become considerably altered, 
being larger, more numerous, and presenting evidences of repro- 
duction. Osteoclasts are absent, except in the larger of these 
spaces, and the process does not seem to be primarily lacunar 
absorption. 
CASES se 
Sapajou (Cebus hypoleucus).—This animal had been in cap- 
tivity several years before being deposited at the Park. Paral- 
ysis was not a feature of this case and reflexes were present in 
the hind limbs. On palpation a considerable alteration in the 
shape of thorax and especially of the sternum was found. The 
animal was killed in the earlv stage of the disease, which probably 
accounts for the absence of anesthesias of the posterior extremi- 
ties. 
