EFFECTS OF THIRST — ALBINO RATS 419 



a loss of 52.7 per cent. In the rat (Si. 2), after total inanition, 

 the corresponding apparent loss in weight of the pancreas (table 

 1) is 58.6 per cent. Thus the relative loss appears to be similar 

 to that in the combined salivary glands, though somewhat less 

 during chronic inanition. 



In a dog on dry diet with loss of 20.7 per cent in body weight, 

 Falck and Scheffer ('54) found a loss of 36.1 per cent in the weight 

 of the pancreas. Similarly, Lukjanow ('89) observed a loss of 

 54.4 per cent in the weight of the pancreas (body weight, —34 

 per cent) in pigeons after total inanition. These results are in 

 fair agreement with my observations on rats. Atrophy of the 

 pancreas was also observed by McCarrison ('19) in pigeons and 

 monkeys on vitamine-deficient diets. 



Stomach and intestines 



In two cases of acute thirst ulceration and hemorrhage of the 

 stomach were observed in the mucosa near the cardia. The 

 digestive tube, from the level of the diaphragm to the anus, was 

 removed and separated from the pancreas, mesentery, etc., and 

 weighed with and without contents. 



The stomach and intestines, including their contents in acute 

 thirst, show an apparent loss of 36.4 per cent in average weight, 

 and in chronic thirst a loss of 28.3 per cent (table 2). In the rat 

 (Si. 2) after total inanition (table 1) the apparent loss is greater, 

 amounting to 52.1 per cent. 



The stomach and intestines, without contents, in the acute- 

 thirst series show a loss of 29.1 per cent in average weight, and 

 in the chronic-thirst series a loss of 31.8 per cent (table 2). In 

 the rat (Si. 2) after total inanition (table 1) the corresponding 

 apparent loss is 20.3 per cent. In all cases the loss is relatively 

 less in the stomach and intestines than in the body as a whole. 



In a dog on dry diet with loss of 20.7 per cent in body weight, 

 Falck and Scheffer ('54) noted an apparent loss of 7.6 per cent in 

 the weight of the stomach and of 17.9 per cent in that of the 

 intestines. In three dogs after experimental diarrhea with loss 

 of 22 to 30 per cent in body weight, Tobler ('10) found apparent 

 losses of 2.5 to 34.5 per cent in the weight of intestinal tract. 



