66 DR ANDERSON ON CODEINE, AND 
10:050 grains of the crystallised oxalate lost, at 212°, 0°704 grains of 
water = 7:00 per cent., corresponding to three equivalents of water, which re- 
quires 7:27 per cent. The formula of the crystallised salt is, therefore, C,, H,, NO, 
HO C,0,+3 HO. 
Hydrosulphocyanate of Codeine-—This salt has been already examined by 
DotiFus;* but I have prepared it, and repeated the analysis, with results differ- 
ing somewhat from those obtained by him. It is readily obtained by mixing 
solutions of hydrochlorate of codeine and of sulphocyanide of potassium, and is 
slowly deposited in beautiful radiated needles. 
14:285 ++. carbonic acid, and 
6-164 grains of hydrosulphocyanate, dried at 212°, gave 
3°543 «-- water. 
7:444 grains, burnt with nitre and carbonate of soda, gave 4899 grains of 
sulphate of baryta. 
These results correspond with the formula C,, H,, NO, HC,NS,, as is shewn 
by the following per centage calculation, to which I have added the results 
obtained by DotLFus :— 

Experiment. Calculation. 
DOLLFUs. 
Carbon, ; p : 62°30 63:20 63°68 Crs 228 
Hydrogen, . : ‘ 613 6°38 6:14 H,, 22 
Nitrogen, é : ae os 7:82 N, 28 
Oxygen, : : i ne dp 13°43 O, 48 
Sulphur, 7 y - ane 9°04 8:93 Ss, 82 
100-00 358 
11-613 grains of the crystallised salt, dried at 212°, lost 0:288 grains of water 
=2-47 per cent., corresponding to one equivalent of water, the calculation of 
which gives 2°45 per cent. 
In the analysis of Dottrus, there is manifestly a loss of carbon, as the results 
are quite incompatible with those of the base and its other salts. In the same 
paper Dotirus has also determined the amount of sulphocyanogen by precipitation 
with silver, and the results obtained agree better with the formula given above 
than with his own. 
Chloride of Platinum and Codeine.—When bichloride of platinum is added to 
a moderately concentrated solution of hydrochlorate of codeine, a pale-yellow, 
pulverulent precipitate is deposited. If this be allowed to stand for some time 
in the solution, or still better, if it be collected on a filter and kept moist, it begins 
to change in its appearance ; specks of darker colour appear in it, and it is gra- 
dually converted into a mass of crystalline grains of an orange-yellow colour. 
The fluid which filters off deposits, on standing, a small quantity of larger grains. 
* Annalen der Chimie und Pharmacie, vol. Ixv., p. 218. 
