
ITS PRODUCTS OF DECOMPOSITION. 73 
Considerable difficulty was experienced in getting it absolutely free from co- 
deine; and the first of the following analyses has given an excess in the carbon :— 

6-119 grains bromocodeine, dried at 212°, gave 
I 12:941 ++ of carbonic acid, and 
3:°000 ++. of water. 
5°940 grains bromocodeine gave 
II 12'461 ... of carbonic acid, and 
2°910 «+. of water. 
5:268 grains gave 2°663 grains of bromide of silver. 
Experiment. Calculation. 
——————— So — ——. 
Er II. 
Carbon, . 2 : 57:67 57:21 57-14 C35 216 
Hydrogen, . c é 5:44 5:44 5:29 H,, 20 
Bromine, . - Z das 21:50 21:16 Br 80 
Nitrogen, . : ~ are wes 3°70 N 14 
Oxygen, . c : ae ee 12-71 O, 48 
100-00 378 
The formula is therefore C,,H,, Br NO,. Bromocodeine is capable of uniting 
with water in two different proportions, as appears by the determination of the 
loss by drying. 
11°784 hier bromocodeine, lost at 212° 0-273, =2-32 per cent. 
9-308 ar ace 0-623, =6-69 ... 
77107 ace on 0-512, = 6°64 
The first of these results eee exactly to one equivalent of water, the 
calculated result for which gives 2°32 per cent. The other two give three equi- 
valents, for which the calculation is 6:66. I am unable now to recollect how 
the bromocodeine used in the first experiment was obtained, but my impression 
is, that it was prepared in exactly the same manner as the rest. 
Hydrochlorate of Bromocodeine is obtained in radiated needles closely re- 
sembling those of hydrochlorate of codeine. 
Hydrobromate of Bromocodeine.—The crystals, which have been mentioned 
as making their appearance during the preparation of bromocodeine, are this 
salt. It is sparingly soluble in cold water, readily soluble in boiling water, and 
is deposited from the solution in small prismatic crystals. It contains two equi- 
valents of water which are not expelled at 212°. 
8-424 orains of hydrobromate, dried at 212°, gave 
13-956 --- of carbonic acid, and 
{ 3985 --- of water. 
Experiment, Calculation. 
a 
Carbon, . . See 45:18 45:28 Ce 216 
Hydrogen, . 5 : “6 5:25 4:84 H,, 23 
Bromine, f : : é oe 33°54 Br, 160 
Nitrogen, : : : os 293° =N 14 
Oxygen, 4 7 - os 13°41 0, 64 

100-00 477 
VOL. XX. PART I. U 
