74 DR ANDERSON ON CODEINE, AND 
The formula of the salt is therefore C,, H,, Br NO, H Br+2 HO. 
Platinochloride of Bromocodeine is precipitated as a pale-yellow powder, 
insoluble in water and alcohol. 
8-126 grains, dried at 212°, gave 1:380 grains platinum. 


Experiment. Calculation. 
Carbon, : : : 2 36:97 Cre 216 
Hydrogen, . - 3 : 3°59 lal 20 
Bromine, . : A J see 13-70 Br 80 
Nitrogen, . 5 . A se 2°39 N 14 
Oxygen, . : : : oo 5-23 O, 48 
Chlorine, ; ; : as 18:23 Cl 106°5 
Platinum, . : ; ‘ 16°98 16°89 Pt 98-7 
100-00 5842 
Tribromocodeine.—By continuing the addition of bromine water beyond the 
point at which bromocodeine is formed, a further action takes place, and a bright- 
yellow precipitate makes its appearance, which at first redissolves in the fluid, 
but after a time becomes permanent, and goes on gradually increasing until a very 
large quantity of bromine has been employed, when at length a point is reached 
at which no further precipitate is produced. If the solution be left till next day, 
however, bromine again causes a precipitate ; and if it be added, as long as anything 
falls, and the solution be again left standing, another precipitate is produced iden- 
tical in all respects with that before obtained, and this may be repeated day after 
day for a very considerable time. The yellow precipitate so obtained is the hydro- 
bromate of tribromocodeine. It is collected on a filter, and washed with water, in 
which it is very sparingly soluble. In order to obtain the base, this substance is 
dissolved in dilute hydrochloric acid and ammonia added, when the tribromoco- 
deine is immediately precipitated as a flocky powder, which is washed with water, 
and purified by solution in alcohol, and precipitation with water. 
Tribromocodeine is thus obtained as a bulky white precipitate, perfectly amor- 
phous, and when dry, more or less gray in its colour. It is insoluble in water 
and ether, but readily soluble in alcohol. It is sparingly soluble in hydrochloric 
acid in the cold, but much more so by boiling. In this process, however, it ap- 
pears to undergo a partial decomposition, as a small quantity is always left in- 
soluble. Heated on platinum foil it becomes brown, and is entirely decomposed 
at its melting point, leaving a coal difficult of incineration. 
The tribromocodeine employed for analysis was purified by a second solution 
in alcohol, and precipitation by ether. It gave the following results :— 
11-665 ... of carbonic acid, and 
8-014 grains of tribromocodeine, dried at 212°, gave 
2645 +.» of water. 
3°55 grains of tribromocodeine gave 3°727 grains bromide of silver. 
