76 DR ANDERSON ON CODEINE, AND 
mating to the experimental numbers, and the recurrence of the results, in portions 
prepared at different times, leaves no doubt that this is their real constitution ; 
and, in all probability, the error may be due to the salt retaining a small excess 
of hydrobromic acid. The constitution is therefore remarkable, and I am not 
aware of any similar salt having been before observed. 
Platinochloride of Tribromocodeine.—Bichloride of platinum throws down 
from solution of tribromocodeine, in hydrochloric acid, this salt, in the form of a 
brownish-yellow powder soluble in water and alcohol. 
5°142 erains of platinum salt, dried at 212°, gave 0-669 grains of platinum. 


Experiment. Calculation. 
Carbon, 29-10 C,, 216 
Hydrogen, 2°55 leh 19 
Bromine, 32°33 Br, 240 
Nitrogen, 1:88 N 14 
Oxygen, 6°57 O 48 
Chlorine, ; te 14:34 Cl 106°5 
Platinum, : 13:07 13-29 Pt 98-7 
100-00 742°2 
I have reason to believe that the action of bromine upon codeine does not ter- 
minate with the production of the base now described ; but its further action did 
not appear to afford any products of a sufficient interest to induce me to prose- 
cute the investigation in this direction. There must also no doubt exist a dibro- 
mocodeine, C,, H,, Br, N O,, but I did not meet with it in the course of my ex- 
periments, and have not made any special attempts to obtain it. 
VI. Action of Chlorine upon Codeine. 
We might anticipate that the action of chlorine upon codeine should be exactly 
similar to that of bromine; but this is not the case, as in place of a simple 
and definite action complex products are immediately obtained. When a current 
of chlorine is passed through an aqueous solution of codeine, the fluid immedi- 
ately acquires a brown colour, which soon becomes very deep, and eventually 
almost black. From this solution ammonia throws down an amorphous, resinous 
base. With chlorine-water the solution also becomes rapidly brown, and a 
similar precipitate is obtained. As there wasno method of determining in either 
of these cases when the action was complete, I did not attempt to examine the 
product. I succeeded better, however, by the action of chlorate of potash, and 
obtained a base corresponding to bromocodeine. 
Chlorocodeine.—For the preparation of chlorocodeine a sufficient quantity of 
codeine is dissolved in an excess of dilute hydrochloric acid, at the temperature of 
about 150° or 160°. Finely-powdered chlorate of potash is then added, and the solu- 
tion agitated. In the course of a few minutes a small quantity of the fluid is 

