536 KSSAYS anp OBSERVATIONS — 
otherways it could not produce thefe ef- 
fects fo inftantaneoufly, (N° 21. and 22.). 
Befides, fince opium thrown into the fto- 
mach and guts of a frog after being de- 
prived of its heart, deftroys the fenfibili- 
ty and moving power of its mufcles equal- 
ly foon, as if the animal had been intire 
(N° 2.); it is plain, that thefe effects can- 
not be owing to the finer parts of the o- 
pium being received into the blood, and 
by its means carried to the feveral muf- 
cles and organs. | 
(0) Nor does a folution of opium in- 
jected into the great guts or cavity of the 
abdomen in dogs produce its effects by 
tranfinitting through the nerves any fub- 
tile effluvia to the fpinal marrow; other- 
ways its operation could not have been 
fo inftantaneous (N° 21. and 22.); nor 
could the fpinal marrow and its nerves 
have recovered their functions fo foon,; 
after the opium was evacuated by a pur- 
gative clyfter, N° 21. 
(p) Ir remains, therefore, that apiani, 
by affecting the extremities of the nerves 
of the parts to which it is applied, does, 
by 
