PHYSICAL AND LITERARY. 303 



EXPERIMENT L {TwoTriah), 



Thirty drops of a folution of opium 

 ^n water * were poured through a tube 

 into the ftomach of a frog. After four 



hours it was fomewhat ftupified, and, if 

 touched, thpugh in the flighteft manner^ 

 pried or fobbed, in a way which I have 

 pbferved this animal to do only when afr 

 fe(5led with opium ; ftill, however, it could 

 leap with force ; nor was the rapidity of 

 the blood in the hind feet fenfibly lefTen* 

 ed. After ten hours, the motion of the 

 blood was lefs rapid; but ftill it could 

 leap. After 22 hours, the blood had al- 

 paoft ceafed from motion ; and, in one 



hour 



•The folution ufed ia this, and all the following ex- 

 periments with opiuni, was prepared hj accurately mix'* 

 ing a drachm of opium with an ounce of cold water in 

 a mortar, and after one day's digertion filtrating the cleac 

 part of the mixture. And I may here, once for alK Ob- 

 ferve, that my experiments are made on full grown 

 frogs, unlsfs where it is otherwife fpecified ; and that, 

 where the fame experiment was repeatedly tried, I de- 

 scribe the meaa refuU of it. 



