3i6 ESSAYS AND OBSERVATIONS 



is flopped. But here we perceive an ohr 

 vious difficulty: For, if we flop the cirr 

 culation in every part of the body by cut- 

 ting out the heart, or flop it in one par- 

 ticular part, fuppofe in the hind legs^ 

 (where it can be done more eafily and cer- 

 tainly than in any other part, by tying 

 the aorta, njena cava, and lymphatics, at 

 the top of the pelvis ;) it is evident that the 

 animal will bedead, or the nerves will have, 

 lofl their energy in a great nieafure, if not 

 intirely, (See preliminary fads 3d, 4th,), 

 before the folution of opium can produce 

 its efFeds in a very obfervable degree, if 

 it be ufed in any of the three common 

 methods which have been defcribed, viz. 

 applied to theikin, or given by the mouthj^ 

 or injeded into the anus. 



(Two Trials) • 



Accordingly, the animal was nQt 

 pbfervably flupified by applying op.iun^ 

 to the ikin of the hind legs, after tying 

 ;he aorta, vena cava, and lymphatics. And 



therefore., 



