322 ESSAYS AND OBSERVATIONS^ 



of the opium in the former cafe, and 

 what was abforbed could go no farther 

 than the auFiele of the heart ; but chiefly 

 and almoft intirely owing to this, that 

 the nerves, after the circulation is (lopped, 

 much more difficultly receive an impref- 

 fion. 



E X P E R. IX. {two Trials), 



I made a ligature around the bafe of 

 the heart, and cut off its ventricle, and 

 then poured 30 drops of the folution of 

 opium under the fkin of the left hind leg 

 and thigh. 



Eight minutes thereafter, its toes were 

 kfs ienfible, and it began to drag the 

 leg without bending its joints. After a 

 quarter of an hour, its toes were quite in- 

 fenfible, and its mufcles only fliewed fome 

 remains of power when the animal made 

 a violent effort, and, within {even minutes 

 more, they were quite paralytic. After 

 40 minutes, it lay ftill unlefs when hurt. 

 After ten minutes more, it could not a6t 



with 



