340 ESSAYS and OBSERVATIONS 



Experiments ivith ardent Spirits, 



EXPERIMENT I. {Four Trials). 



About feventy drops of a mixture of 

 equal parts of white wine and French 

 brandy, which mixture was ufed in all 

 the following experiments on this fubjedl, 

 were applied on fcraped linen, to both the 

 hind extremities of a frog. Seven mi- 

 nutes after this, the animal was obferva- 

 bly afFeded, and its heart beat only 50 

 times in a minute. After a quarter of- 

 an hour, the heart beat only 45 times in 

 a minute ; yet the rapidity of the blood 

 in the hind feet was not very obfervabiy 

 lefTened. After 20 minutes, the heart beat 

 only 40 times in a minute, and the crea- 

 ture was much ftupified. After half an 

 hour,, the heart beat only 35- times in a 

 minute, and evidently with lefs force than 

 natural ; and now the circulation was 

 confiderably lefs rapid in the vejQTels of the 



hind 



