PHYSICAL AND LITERARY. 305 



heart's motion in frogs, near fo foon as opium 

 injeded into their ftomach and guts, or ap- 

 plied to the mufcles and bowels of the lower 

 belly and thrax. 



(h) Altho' a folution of opium applied 

 to the opened thorax and abdomefi of a frog, 

 after decollation and the deftrudion of Iti 

 fpinal marrow, foon weakens or deftrdys the 

 motion of the heart ; yet it does not pro- 

 duce thefe effeds fo fpeedily as when the 

 brain and fpinal marrow are intire, N* it. 

 and 12. In the former cafe, xht ophim cafi 

 only affeA the heart by its topical influence 5 

 in the latter, it not only afts this Way, ' but 

 alfo exerts its powers upon the brain, fpi- 

 nal marrow, and whole nervous fyftem ; 

 and therefore muft produce more fudden 

 efFedis. '^ 



(/j It appears, beyond doubt, from the 

 preceeding experiments, that the heart is not 

 exempted from the power of opium, as the 

 learned Dr. H^/Z^r has affirmed*, but Has 

 its motion deftroyed by it, as well as the o- 

 ther mufcles, only not fo" foon. 8eeN*^'4. 

 and 5. compared with N** 3. 6. 8. & 10. 

 Vol. II. Q_q and 



* A(X. Gotting. vol. ii. p, 147 ^ >54- 



