DICTIONARY OF THE ACTIVE PRINCIPLES OF PLANTS. 



Cinchona rob\i>ta ; a hybrid. 



,, rosolenta ; Cud., Quinamine, Bicinchonine, Homo-cinuhoni- 



dine, etc. 

 „ rubra ; red bark. See also C. succirubra. 

 „ scrobiculata. See Nitida. 



„ SUCCIRUBRA (Red barlO- More Cnd. than Qn., usually about 

 3 to f) per cent, of former to li per cent, of latter (Dr. 

 Paul) ; also Cn. and Quinamine — more of the last named 

 in this variety than in others. Qnd. only trace, or absent. 

 „ tuna. Qn. (5-78, Cnd. 0-40, Cn. 0-:!8, Qnd. 0-lK, amorphous 

 0-42— total, 8-16 per cent.* 

 Pogonopus febrifuga, or Howardia (Bolivian Caseurilla, C. morada). 



Qnd. (no Cnd.), Moradeine, etc. See (32), (33). 

 Remijia pedunculata (Cuprea bark). Qn. (1), Cupreine (21), Homo- 

 quinine 22. Quinamine, etc. (18), (20), Concnsconine, etc. 

 (10), (11), Hydrocinchonine. 

 „ purdieana (Remijia bark). No Quinine nor Cinchonidine ; 

 traces On., also Cinchonamine. Concusconine, Chairamine 

 and analogues (14 to 17), Cinchotine (4 per cent.). 



Croton eluteria (Cascarilla bark), Euphorhku-ew. Casoarillin (28) 

 Bolivian cascarilla, see Pogonopus. 



„ pseudochina. Copalchin (2',0. 

 Cascarilla hexandra. Paricine (2y). 



„ riedeliana (China Califoinica). Californin (31 ). 



The following is a list of the alkaloids and other substances 

 described, aud the order in which they appear. 



(1) QUININE. (4f/) Apocinchonicine 



(2a) Isoqninine. (4e) Diapocinchonine. 



(26) Qiiinicine. (if) Hydrocinchonine. 



(2c) Apoquinine. 



(2rf) Quitenine. 



(2f) Hydroquinine. 



(3) CINCHONINE. 



(4ff) Isocinchonine. 



(46) Cinchonetine. 



(4c) Apocinchonine. 



For 



(4,17) Cincholeuponic acid. 



(4/() Cinchonibine. 



(40 Cinchonifine. 



(4/) Oinchonigine. 



(4/i.') Cinchoniline. 



(4/) Alpha-oxy-cinchonine. 



(4)h) Betn-oxy-cinchonine. 



(All) Cinchonicine. 

 (4o) Carthagine. 

 (4/1) Cinchotine. 

 (■If/) Dicinchonine. 

 (.^1) QUINIDINE. 

 (i'jii) Apiiquinidine. 

 (66) Hydroquinidine. 

 ((V) Quitenidine. 

 ((>(/) Iso(|ninidine. 



(7) CINCHONIDINE. 

 (7a) Isocinchonidine. 

 (76) Apocinchonidine. 

 (7c) Cinchamidine. 

 (7rf) Homocinchonidine. 



(8) Aricine. 



(9) Ciisconine. 

 (\hi) Cuscoiiidine. 

 (it6) Cuscamidine. 



(10) Concusconine. 



(11) Concuscouidine. 



(12) Cuscamine. 



(13) Chairamine. 



(14) Conchairamiue. 



(1.')) Chairamidine. 

 (10) Conchairamidine. 

 (17) Quinamine. 

 (18«) Apoquinamine. 

 (186) Quinamicine. 

 (18c) Quinamidine. 

 (1!)) Conquinamine. 



(20) Cupreine. 



(21) Homoqiiinine. 



(22) Cinchonamine. 



(23) Quinoidine. 



(24) Quinetum. 

 (2r») Paricine. 

 (2(i) Qiiinovin. 

 (2rio) Beta-quinovin. 



(27) Quinovic acid. 



(28) Cascarillin. 



(29) Copalchin. 

 (.?0) Lignoin. 



(31) Californin. 



(32) Moradeine 



(33) Moradin. 



(34) Javanine. 



Aualvsis of New Grcimda Barks, liy D. Howanl. 



(1) QUININE A., C„„H„,N„0.,+ 1 or 3H„0 ; usually amorphous, but crys- 

 talline needles, containing 3H.^0, are gradually formed from the precipi- 

 tate by ammonia, and crystals are also obtainable from solutions in 

 petroleum ether and benzene, but not from ether. M.P. 171°-172' when 

 anhydrous, 120° hydrate, or 67° the trihydrate (0. Hesse) ; laevo-rotatory, 

 [a]K= -141 3 in alcohol (De Vrij) ; very bitter ; fluorescent in acid solu- 

 tion ; alkaline reaction. 



Solubility : 1 in 1,6G7 cold water and 1 in 902 boiling (Sestini), or 1 in 

 364 cold and 1 in 2(57 boiling (Duplos) ; 1 in 2 alcohol of sp. gr. 0'82, and 

 even easier soluble at boiling heat ; 1 in 23 cold ether (Vandenburg), or 

 1 in 60 (Merck), but much more readily when fre-hlv precipitated ; very 

 soluble in chloroform, about 1 in 18 (Pettenkofer) : also dissolved by 

 benzene, amyl alcohol, petroleum ether, carbon bisulphide, and oils. It 

 is removed from alkaline solutions by petroleum ether, benzene, ether, 

 chloroform, and amyl alcohol. 



The salts are generally less soluble than those of Cinchonine. 



