TlHTK.INARV Or TlIK ACTIVE I'UINCI I'M'.S OK PLANTS. 



37 



Colour tests : ('oncentrated sulphuric acid, intense green. 

 Nitric acid, as Chairamidine (!.')) above. 

 Fruhde's reagent, intense green. 



(17) qUINAMINE A., Ci.jH^jN.^O.. Crystallize.s in prisms (no crystalline 

 hydrate; M.P. 172° ; dextro-rotatory ( + 1(U'5°) ; tasteless, though salts 

 are bitter : iioii-fluoresceut. 



Soluble in l,riir. parts water at KV C, 105 alcohol at ■20° C, 4K ether 

 at Ui° ('., in chloroform, boiling benzene, and petroleum ether. 



Precipitated by gold chloride, pale yellow, changing to red with 

 reduction of gold. 



(18a) APOQUINAMINE A. From the above by boiling with acids. 



(18i) QUINAMICINE A., C„H._,jN.A- Formed together with (]8r) from 

 Quinamine bv beating to l.^O' with hydrochloric acid in sealed tube, 

 (.'rvstalline ; M.P. lOil". 



Soluble in alcohol, ether, and chloroform. 

 Precipitants : 



Alkaline hydrates ^ 



„ carbonates ;-insol. in excess, 

 bicarbonates I 

 Ammonia, amorphou.«, becoming crystalline ; insol. in excess. 

 Gold chloride, amorphnus ; yellow if pure, or purple if containing 



Qninamidirie. 

 Potassium iodide. 

 Salicylate ammonia. 

 Oxalate ,, 



Sodium chloride. 

 Acids (hydrochloric, nitric, or sulphuric) also give precipitates. 



(IHc) QUINAMIDINE A. Formed in the preparation of the above, from 

 which it is distinguished by giving 



No pp. with bicarbonates of the alkalies. 

 The gold chloride pp. is purple. 



(19) CONQUINAMINE A., C,„H„jN„0.,- Triclinic prisms ; M.P. 121° ; 

 dextro-rotatory (+204'). 



Soluble in alcohol, ether, chloroform, benzene, carbon bisulphide, and 

 with difficulty in water. 



Precipitate by gold chloiide is yellow, becoming purple. 



(20) CUPREINE A., C,:,H,...N,0- and with 2H.2O. Crystallizes in prisms 



from ether ; becomes anhydrous at I'lO'-Mb", subsequently melting at 

 l'J8° ; alkaline reaction, Icevo rotatory (= — 17;")°). 

 Soluble in alcohol, but with difficulty in ether or chloroform. 

 It is not removed from a 10 per cent, soda solution, but from 

 ammoni.ical liquids by immiscible solvents. 

 Precipitants : 



Alkaline hydrate, soluble in excess. 



Ammonia, slightly soluble in excess. 



Ferric chloride, dark brown coloration. 



Platinum chloride, pp. difficultly soluble. The dry double salt 



becomes dark gieen on heating. 

 Potassium sulphocyanide, cloud changing gradually to crys. pp. 

 Chlorine water, etc. (thalleioquin reaction), as Quinine. 



(21 ) HOMOQUININE A. (Ultraquinine), C,„H„.,N.,0./C.,„H.,,N._,0.,. A com- 

 pound of <^)uinine and Cupreine in molecular proportions (Paul and 

 Cownley). Pearly ])rismatic crystals in stellar groups ; M.P. 177" ; liEvo- 

 rotatory [a] .1= — 221° ; fluorescent (the acid salts) ; strongly alkaline. 



Soluble in alcohol and chloroform, but with difficulty in ether unless 

 freshly jirecipitated. 

 Reactions : 



Ammonia, dissolves. Rochelle salt, pp. with concentrated solutions. 



[No pp. iodo-potassic iodide.] 



Concentrated sulphuric acid with potass, bichromate, deep green. 



Concentrated sulphuric acid alone ) , . ■, „ 



..^. >■ do not decompose. 



„ nitric „ ,, I '^ 



Gives the thalleioquin reaction (chlorine water, then ammonia). 



The soda hydrate pp. contains Quinine and (Jupreine, only the former 



being removable on shaking with ether. 



(22) CINCHONAMINE A., C,gH.jN,0. Hexagonal prisms (no crystalline 

 hydrate) ; INI. P. lOfi^ ; dextro-rotatory (+121°) ; bitter, poisonous. 



Soluble in alcohol, ether, chloroform, benzene, and carbon bisulphide ; 

 difficultly in water and petroleum ether. Hydrochloride sparingly soluble. 



Reactions: No colour with ferric chloride, nor thalleioquin test 

 (chlorine water, etc.). 



(23) QUINOIDINE and (24) QUINETUM are mixtures; the former con- 

 taining principally Quinicine (see 2i) with Cinchonicine (see 4/i) ; and 

 the latter the alkaloids of red bark. 



(2ro PARICINE A., C,cH,8N„0, from China Succirubra and Cascarilla 



