49 



soluble in water and partly of an oily nature. — Found by Howard 

 in the bark of Cinchona succh-ubra.] 



Cinchoni(lill=C2o H12 NO. In the Quina rubra granatensis 

 (called originally Quina pseudoregia), from Cinchona succirubra, C. 

 Calisaya, C. officinalis, C. lancifolia. Exhaust the bark reduced 

 to powder, with water acidulated by hydrochloric acid, treat 

 the solution with milk of lime, collect the deposit, dry, pulverise, 

 draw out with alcohol, evaporate the fluid, let crystallise and 

 purify by recrystallising in alcohol. — Forms colourless, long, 

 shining prisms ; fuses at 167 to 170° and decomposes in higher 

 temperatures ; without smell, of bitter taste ; becomes electric by 

 friction; dissolves in 3287 parts cold, and in 596 parts boiling 

 water, in 88 parts cold and in 19 parts boiling alcohol of 0.833, 

 in 398 parts cold ether of 0'740 ; the alcoholic solution has an 

 alkaline reaction ; dissolves readily in diluted acids, also in 

 concentrated sulphuric acid without change ; dissolves colourless 

 in chlorine-water, and ammonia prodvices in the solution a grey- 

 white precipitate, sokible in an excess of ammonia with pale 

 sherry colour. It saturates the acids completely, and forms well 

 crystallisable salts, which are permanently precipitated by caustic 

 alkalies and their carbonates, phosphate of soda, chloride of 

 mercury, chloride of platinum, chloride of gold, iodide of 

 potassium, sulphocyanide of potassium, nitrate of palladium and 

 by tannic acid. 



Ciilclioiii(lin=: Pasteur's Quinidin. 



CillCll01lill=C2o H12 NO. Prevails in the gi-ey and brown 

 and especially in the Huanoko Quina-barks, from Cinchona 

 micrantha, C. nitida, C. Peruviana, C. Pahudiana, C. 

 scrobiculata, C. cordifolia. Digest with water acidulated with 

 hydrochloric acid, press, concentrate the extracts, filter, precipitate 

 with ley of soda, wash the deposit and dissolve it in acetic acid, 

 precipitate again, dry the deposit, boil with alcohol and allow to 

 crystallise. — Forms white pellucid needles of alkaline reaction, of 

 slightly bitter taste, fuses only when decomposition is setting in, 

 and evaporates partly undecomposed (according to others : it fuses 

 at 150 to 160° and sublimates partly in white needles); dissolves 

 in 3670 parts cold, and in 2500 pai-ts boiling water, in 126 parts 

 absolute, and in 115 parts alcohol of 90% at 15°, in 40 parts 

 boiling alcohol, in 600 parts cold and in 470 parts boiling ether, 

 in 23 parts chloroform, little in oils ; dissolves colourless in chlorine- 

 water, and is precipitated white by ammonia ; dissolves colourless 

 in concentrated sulphuric acid and is not coloured on heating ; 

 insoluble in alkalies. Neutralises the acids and yields mostly 

 crystallisable salts, the solutions of which turn dark red- 

 brown in the sunlight. 



