250 



3 — Do 3 , — C h 1 o r o i n d o p h e n a z i ne 



has been ubtained by the following method. 20 gr. of acetylisatin 

 were dissolved in hut acetic acid and a corresponding quantity uf 

 chloro-o-phenylenediamine chlorhydrate and acétate of sodium added. 

 After some time a precipitate bas been formed; without filtering 

 off the latter, water has been added. the mixture rendered alkaline, 

 boiled for 15 minutes and filtered. The insoluble part represents 

 ß-chloroindophenazine, which is purified by crystallisation from 

 acetic acid. Obtained yellowish needles melting at 310". soluble 

 with difficulty in acetic acid. very little scjluble in alcohol. benzène 

 aceton and ether. 



Analysis: 



{).{032 gr. gave 15-7 m-^ N (t^lS" p=730 ww.) 



found l6-86»/„ N 







calcul, for C^ H^ N, Cl — 16-67 



fi-o-a m i n o- 2-P h e n y 1 - o- H y d r o x y - 6(7)-c h 1 o r o c h i n o x a 1 i n e 



In Order to obtain this substance the filtrate from fi-chloro- 

 indophenazine is acidulated and the precipitate containiug two iso- 

 meric o-acetamino-phenyl-hydroxychlorochinoxalines dissolved in 

 conc. hydrochloric acid and the solution heated on a water bath for 

 six hours. After that the solution was diluted with water, filtered; 

 neutralised by adding an alkali. In order to separate the two iso- 

 merico-amino-phenyl-hydroxy-chlorochinoxalines the precipitate nien- 

 tioned is crystallised from alcohol. The more soluble part melting 

 at 229" — 230" and cry.stallising in orange needles we will call the 

 ß-moditication, bec.ause it yields ß-chloro-indcjphenazine on being 

 boiled with glacial acetic acid. It is easily soluble in aceton. with 

 difficulty in benzène, Chloroform and ether. Its solution in conc. 

 hydrochloric acid gives a red coloration with ether. The hydrochlo- 

 ride is white. 



Analysis: 



0.1061 gr. gave 14-2 em^ N (t=10-5ö p=740 »mm) 



found 15-56»/o N 

 calcul. forC,, H,„ N3 Cl 15-51 „ „ 



