254 



o - H y d r o X y - 2 - p h e n y 1 - 3 - h y d r o X y - 7 (&)- c h 1 o r o- 

 c h i n o X a 1 i n e. 



In order to obtain this Compound we proceeded as follows: 

 15 gr. of isatin were converted into isatic acid under conditions 

 previously related '), and diazotised in the well known manner. The 

 diazobody was next converted into o-hydroxy-benzjyl-fonnic acid 

 by boiling it with a diluted solution of sulpliuric acid and finally 

 the o-hydroxy-benzyl-forniic acid isolated by extraction with ether. 

 The condensation with o-chloroplienylenediamine takes place easily 

 at the température of the boil of the aqueous solutions of the re- 

 acting bodies. The chinusaline Compound obtained was finally puri- 

 fied by crystallising from alcohol. We obtained yellow needles, 

 melting at286 — 7''wbicli dissolve easily in caustic alkalis, conc. acids 

 and in boiling alcohol, but with difficulty in benzène, ether and 

 Chloroform. 



Analysis: 

 0.1702 gr. gave 15.4 cm' N (t = 17.5» p. 757» mm) 

 found 10 43 7o î^' 

 calcul, for Ci^HgOaNa Cl 10.26 o/,, N 



Sulphonic acid of o-hjTdroxy-2-phenyl-3-hydroxy- 

 -7(-6)- chlorochinoxaline 



is formed by heating the sulphuric acid solution of the chi- 

 noxaline Compound on the water bath. The formerly dark reddish 

 brown solution changes gradually its colour to a yellow one. The pro- 

 duct of sulphonation can be isolated by pouring the warm sulphuric 

 acid solution into water and adding sodium chloride. The sodium 

 sait formed can be purified by crystallising from boiling water. It 

 contains thi'ee molécules of water of crystallisation: 



1.4029 gr. lost on being heated to 125" 0.1754 gr. 



found 12.52''/„ H.O 



calcul, for CiJîgNoOa Cl. SOgNa + SH.p 12.35o/„H20 



') liull. lut. de l'Acad. des Sciences de t'racovie. Classe des Sciences iiia- 

 thém. et uatiir., 1901, 303. 



