K 
a 
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P 
PRODUCED BY DISTILLATION OF CINCHONINE. 323 
crystalline mass, which on solution in water and re-evaporation becomes lighter 
in colour. The nitrate in this state cannot be obtained in the form of a dry or 
pulverulent salt, in consequence of the presence of an impurity which renders it 
readily fusible at 212°. But ifthe salt is pressed repeatedly between folds of 
blotting paper, and then crystallized from alcohol, fine hard prisms are obtained, 
quite infusible at 212°, and without the slightest tendency to deliquesce. As a 
little colouring matter was still retained, rendering the salt yellow, the crystals 
were pulverized and washed with ether, in which they were nearly insoluble; the 
purified salt gave, on combustion, the numbers annexed. It should be stated, that 
the first analysis was made upon a mixture of two crops, the second of which 
was obtained by evaporating the mother liquor of the first, the second and third 
analyses were made upon the first crop of crystals. 
6-840 grains of nitrate of lepidine (mixture of two crops of crystals) gave 
I. < 14-470 carbonic acid and 
3035 =... water. 
6855 grains of nitrate of lepidine (first crop of crystals) gave 
II. < 14680 ... carbonic acid, and 
3°025 =... water. 
6-340 grains of nitrate of lepidine (first crop of crystals) gave 
IIi.4 18540  ... carbonic acid, and 
2845 ... water. 
Experiment. Calculation. 
i Ty IIL. Mean. 
Carbon, - 57°69 58°40 58-24 58:11 58°25 Cro 120 
Hydrogen, . 4:93 4-90 4:98 4:93 4:86 H,, 10 
Nitrogen, . Te 2: Es dis 13°59 N, 28 
Oxygen, é ie ae des ae 23°30 O, 48 
100-00 206 
Hydrochlorate of Lepidine.—This salt is obtainable without difficulty in small 
white needles. The reason that former experimenters found so much time and 
trouble necessary to obtain crystals, was the presence of the more volatile bases, 
which, strange to say, yield crystalline salts with far greater difficulty than either 
chinoline or lepidine. The crystals of hydrochlorate of lepidine are quite infusible 
at 212°. An analysis gave the following result :— 
7-630 grains of hydrochlorate of lepidine, dried at 212°, gave 
6:060 ... chloride of silver. 
giving a percentage of 19-64 of chlorine, being exactly the quantity required for 
the hydrochlorate of lepidine, as will appear from the annexed comparison with 
the theoretical percentages. 
Experiment. Calculation. 
a aaa 
Carbon, : : We 66°85 Coo 120 
Hydrogen, . 5 BAS 5:57 H,, 10 
Nitrogen, . ; obs 7-80 N 14 
Chlorine, . ‘ 19°65 19-78 Cl 35°5 
