on the Proteolytic Action of Pepsin-hydrochloric acid. 107 
per cent.; with quinine sulphate, slight acceleration was obtained. 
Strychnine and narcotine, in very small quantity, gave slight accel- 
eration. Dr. H. v. Boeck* states, that quinine is without influence 
on the activity of pepsin. 
In our experiments, using larger amounts of the alkaloid salts, 
retardation is very pronounced, doubtless due in part to replacement 
of the sulphuric acid of the salts by the acid of the gastric juice. 
Undigested Fibrin Relative proteo- 
Alkaloid salt. resiaue. digested. lytic action. 
0 0°3555 gram. 64°45 per cent. 100°0 
(Sr)p . H,SO, +6H,0. 
0°5 per cent. 0°6825 31°75 49°2 
1-0 0°8213 17°87 27-7 
(Br), . H,SO, +H,0. 
0°5 05685 43°15 66°9 
10 0°7700 23°00 35°6 
(At). . H,S0,. 
0°5 0°6412 35°88 55°6 
(Q)..H,SO, +7H,0. 
0°5 0°6606 33°94 §2°6 
(Ci)p + H,SO, +2H,0. 
~—05 ‘ 0°6885 31°15 48°3 
(Mo),. H,SO, +5H,0. 
0:5 0°6225 27-15 58°5 
(Na), . H,SO, + H,0. 
0°5 0°6365 36°35 56°4 
Percentage retardation of the alkaloid salts (0°5 per cent.) 
MURV CHIMING nae easels ons) ros heen eae etal eae 50°8 
BEG Cees hoe ee ee She a ee ane Fre ft eem Shee 2 ea ee Soul 
Atropine _ shee Ms. Se Seale Ses SaaS 44°4 
Outlines Sze ssee - Su. ss ci seide ee Cele ates 47-4. 
Cinghonme ts... Se ssee soso Se aetna ee ee ae 517 
Morphine -...-- Pee Se ee sae sets eos ae wie iets 41°5 
INARCOMMOM Ste ieee Soke er Mone SP ee hes Se 43°6 
* Zeitschrift fiir Biologie, vol. vii, p. 428. 
