114 Chittenden and Cummins—Influence of various Substances 
Manyanous chloride. 
Following are the results obtained with this salt : 
Undigested Fibrin Relative proteo- 
MnCly,. residue. digested. lytic action. 
0 0°5215 gram. 47°85 per cent. 100-0 
0-005 per cent. 0°5201 47-99 100°3 
0°050 0°5139 48°61 101°6 
0°100 0°5483 45°17 94:4 
0:500 0°6807 3193 66°7 
Comparing the influence of this salt on the proteolytic action of 
trypsin, with the results obtained with the closely related iron salts, 
it is seen that the manganese salt has a far less retarding influ- 
ence than the latter; a fact which agrees with what was observed 
in studying its action on pepsin-hydrochloric acid. 
Consequently, manganese salts, in so far as they are adapted to 
replace iron salts as therapeutic agents, are apparently less liable to 
interfere with normal digestive action. 
Zine sulphate. 
Undigested Fibrin Relative proteo- 
ZnS04+7H20. residue. digested. lytic action. 
0 _ 0°5035 gram. 49°65 per cent. 100°0 
0°005 per cent. 05175 48°25 97°2 
0°025 0°53805 41°95 84°5 
0°050 0°6802 31°98 64°4 
0100 0°8301 16°99 34:2 
The action of this salt on trypsin is, both in character and extent, 
similar to its action on the amylolytic ferment of saliva. Com- 
pared with pepsin-hydrochloric acid, however, the action of the salt 
is seen to be more energetic on the pancreatic ferment. 
Barium chloride. 
The following results were obtained : 
Undigested Fibrin Relative proteo- 
BaCl,.+2H,0. residue. digested. lytic action. 
0 0°3710 gram. 62°90 per cent. 100°0 
0°05 per cent. 0°3515 64°85 103°1 
0°5 0°3885 61°15 97-2 
3°0 0°4986 50°14 19°7 
With this salt a slight acceleration in proteolytic action is to be 
seen with 0°05 per cent., while the larger amounts cause noticeable 
retardation. | 
Magnesium sulphate. 
Undigested Fibrin Relative proteo- 
MgS0O,4+7H20. residue. digested. lytie action. 
0 0°3495 gram. 65°05 per cent. 100°0 
0°05 per cent. 0°3541 64°59 99°3 
0°5 03810 61°90 951 ~ 
3°0 04706 52°94 813 
