of Sugar in the Liver, in the presence of Peptones. 195 
the sugar, is not at all equal to the figures representing total carbohy- 
drates, being in every instance considerably less than the latter. 
Thus in Experiment V, the amount of total carbohydrates is in A 
(with peptones) 10°17 per cent., while the sum of sugar‘and glyco- 
gen calculated as dextrose is but 8°29 per cent.; a deficit of 1°88 per 
cent. In B, likewise, where peptones are not present, there is a sim- 
ilar deficit, amounting in this case to 1:27 per cent. [t is not to be 
supposed that such a deficiency could in any manner arise from 
errors of analysis and the most natural supposition is that the sugar, 
determined and calculated as dextrose, might be of lower reducing 
power ; or in other words that it might consist of maltose instead of 
dextrose, or rather, of a mixture of maltose and dextrose or of a 
soluble dextrin. O. Nasse* has stated that the dead liver contains 
dextrose, or a sugar whose reducing power is not increased by heat- 
ing with dilute sulphuric acid. Seegen and Kratschmer} also state 
that the dead liver contains dextrose, and further, that the liver sugar 
is exclusively dextrose. This opinion is based mainly upon the fact 
that the fluid obtained from a calf’s liver by pressure, yielded by 
dialysis and subsequent treatment with alcohol, a saccharine body, 
‘which on the addition of an alcoholic solution of potash was converted 
into the known dextrose-potash compound. Musculus and V. Mering,f 
however, claim that in addition to dextrose, the dead liver also con- 
tains maltose. This sugar they detected twice; once in the dead 
liver of a dog, 1 hour after death, and again, also in a dog’s liver, 5 
hours after death. In both cases dextrose was likewise present. Dex- 
trin they were not able to detect with certainty, but they consider 
that the liver ferment also forms this body, intermediate between 
glycogen and the sugars. E. Kiilz§ has also prepared from the dead 
livers of dogs pure dextrose, but he does not conclude definitely as 
to the presence of dextrin and maltose. It is to be seen, therefore, 
that while there is unanimity of opinion regarding the presence of 
dextrose, there is less certainty regarding the presence of the lower 
reducing sugar, maltose. 
_ We have therefore, carefully examined the nature of the sugar 
remaining in the alcoholic filtrate after the precipitation of glycogen, 
and we find, in almost every instance, that the saccharine body there 
* Bemerkungen zur Physiologie der Kohlehydrate. Pfliiger’s Archiv, vol. xiv, p. 473 
+ Die Natur des Leberzucker. Pfliiger’s Archiv, vol. xxii, p. 214. 
} Ueber die Umwandlung yon Starke und Glycogen durch Diastas, Speichel, Pan- 
creas und Leberferment. Zeitschrift fiir physiologische Chemie, vol. ii, p. 417. 
§ Ueber die Natur des Zuckers in der todtenstarren Leber. Pfliiger’s Archiv, vol. 
XXiv, p. 52. 
