XIV.—Guosviry anp GLosuLose Bopirs.* By W. Ktung, Pro- 
fessor of Physiology in the University of Heidelberg, and 
R. H. CuirrenpeEn. 
Tue following investigation is a continuation of our previous 
-work with the albumose bodies,+ and constitutes the commencement 
of a study of the various primary cleavage products, formed by the 
action of pepsin from the better characterized and purer albumins. 
Our work in this direction was at first begun with the albuminous 
bodies occurring in blood serum, egg albumin, and in fibrin and 
from the results then obtained we were led to the conviction that an 
extension of the work to the single albumins was necessary, particu- 
larly to serum albumin, globulin and myosin. In the meantime, our 
first conjecture that hemialbumose might possibly be a mixture, had 
been established and led finally to the isolation of the albumose 
bodies of fibrin.§ At this stage of our work, fibrin was the only 
albuminous material employed because it was the simplest to prepare, 
was easily digestible, and hitherto had been mostly used in diges- 
tion experiments. These practical considerations, to which must be 
added the fact that fibrin albumose was later found as a commercial 
article, were joined with the advantage of being able to make use of, 
and at the same time extend, the discoveries in ‘the chemistry of 
digestion which have for decades been made with this particular 
albuminous material. Other advantages for the use of fibrin in this 
connection cannot well be claimed, since its peculiar position be- 
tween the genuine and the coagulated albumins, its contamination 
with globulin and the presence of nuclein and other components of 
the white blood corpuscles tend to render it perhaps least fitted for 
use in an exact study of albumin cleavage; and since fibrin is of 
importance as a food stuff mainly in the form of the commercial so- 
called peptone, there are many reasons for proceeding to the study 
of other digestible substances for further results. 
* This and the following article were originally published in the Zeitschrift fir 
Biologie, Band xxii. They are republished here to render the series complete in 
Knglish. + See Amer. Chem. Jour., vol. vi, p. 3. 
{ Zeitschrift fiir Biolopie, Band xix, p. 159. § Tbid., xx, p. 11. 
