Antimony in the organs and tissues. 281 
this method to antimoniacal urine, we found it possible to recover the 
antimony without loss. The following results testify to the accuracy 
of the method: 
In each experiment 25 ¢.c. of normal urine were employed, to which 
was added a number of cubic centimetres of the standard antimony 
solution and then 1 ¢.c. of pure dilute sulphuric acid, after which the 
solution was connected with the battery. 
Standard Sb 
Solution in Theoretical Amount Sb Duration of 
25 c. c. urine. amount Sb, found. electrolysis. 
OKewe: 0:0075 gram. 0:0075 gram. 48 hours. 
LO” .<° 00075 ** 00074 24 =< 
il) 46 00075 = ** 00074 <* ORs 
3) ae 0:003875 * 00088 =“ 1S) 6 
Opec 0-00375 <** 0:0037  <* 1S? 3 
iy ah 0-00375  <* 0:0086 << LB Ty cite 
Diss 0-00225 <¢ 0:0024 < HO Wess 
ies 00015 ** 0:0018  «* PAU Bo 
a ae 00015  « 0-0016  « iS eas 
Ry 3S 0-00075 ** 0:0008  «* Gb Es 
Doubtless all of these results could have been obtained equally as 
well in a very much shorter time, but most of the solutions were con- 
nected with the battery at night and allowed to run until morning, 
or whenever convenient. The method is evidently very accurate 
when applied in this manner, and we have made use of it very satis- 
factorily, even with 150 c.c. of urine, using in this case a platinum 
dish of 200 c. ¢. capacity as the negative electrode. 
2. Relative distribution of absorbed antimony. 
As already stated, the object sought in the following experiments 
was to ascertain the relative distribution of antimony under varying 
conditions; particularly, variations in the form of the poison, as its 
solubility or insolubility ; in the method of introduction, as per 
mouth, rectum or sub-cutaneously; and lastly in the length of time 
during which the poison is being taken, whether in one large dose or 
in many small ones frequently repeated. All of these points we have 
endeavored to cover in the experiments about to be described. 
Experiment I. 
Hypodermic injection of a solution of tartar emetic. 
0120 gram of tartar emetic, dissolved in a little water, was intro- 
duced under the skin (right thigh) of a cat weighing 1262 grams. 
TRANS. Conn. Acap., Vou. VII. 36 Nov., 1886, 
