and Inorganic Substances on Gas Metabolism. 435 
EXPERIMENT WITH CINCHONIDINE. 
Normal period, without cinchonidine sulphate. 
|Oxalic acid to Bo | : ; | eee S 
neutralize ba- | = a ze a cS) a Beste a 2 
Date. ryta solution.) @© 5 | Fo | os Sg = S 
8 [rs Eid ae) = ap 2 
June 24. | | a.) | Som te ef oe h B 
italia sc Aven es Se a Sey eee 
ge )22°) e2 ea) 2s | se | st |e. 
eenlie SOS. eit tes ij) )) ee 
A. M. | 
9:00 to 9:30 =| 106 | 28:8 | 39:'4 | 50°2 |  10°8 218°3) 545°8 | 36-4 
9:56 to 10-26 | 11-2 291 40-3 50-2) 9:9 | 2001 | 500°3 | 37-4 
| 
10:47 to 11:17 | 12:0 | 29-0] 41:0 | 50:2) 9-2 185°9 | 465°0 | 38-1 
11:38 to 12:08 | 106 28-7 | 39:3 | 50-2 | 10-9 220°3 | 550°9 | 36:3 
2:03 to 2:38 | 103 285 | 888) 50-2 11-4 | 280-4 | s76xr | 36-9 
2:51 to 3:21 | 9-4 | 28-2| 876 | 502) 12:6 | 2549 | 6368 | 37-1 
$4210 4:12 | 9-7 | 28°5 | 38-2 | 50°2 |. 12:0 | 242°5 | 606-5 |: 37-0 
4:30 to 5:00 | «9-7 | 285 | B82 502 120 | 2425 6065 | 36-4 
Average, | 10:5 | 28-6 | 30-1 | 50-21 11-41 | 2043 | s6z0 | 37-0. 
June 25. With cinchonidine sulphate. 
A. M. 
9:03 to 9:33. =: 10°8 | 286 39-4 | 502) 10-8 | 2183 | 5458 38-6 
9:58 to 10:28 11-4 | 28-9 40:3 | 50:2 9:9 | 200-1 | 500-3 386 
10:53 to 11:23 11:1 | 28-7 | 398 | 502 10-4 | 210-2 5286 386 
1148 to 12:18 | 11-6 | 28-7 40:3 | 50-2 9:9 | 2001 | 500°3 | 38-7 
P. M. | 
2:04 to 2:34 =| 11:1} 28°8 | 39:9 | 50:2! 10°83 208°2 | 520°5 | 38-9 
2:59 to 8:29 | 11°5 | 29:0 | 40:°5| 50:2) 9:7 | 196-0 | 490-2 | 39-0 
3:56 to 4:26 , 11°6 | 29:0 | 40°6 | 50:2) 96 194°0 | 485'2 | 39-0 
4:50 to 5:20 12-1 | 29-1") 41:2 )--50-°3. |) 920 181°9 | 454°8 | 89-1 
Average, 11-4 | 28°8 | 40-2 | 50:2 | 10:0 201°1 | 502°8 | 38:8 
Following are the average daily amounts of carbonic acid excreted, 
expressed in milligrams per 37:5 litres of aspirated air, together with 
the average body temperature. 
_ June 24, Bet OB. 561:0 milligrams CO,:. 
tee Oh, 38°8 502'8 " ie 
Following are the doses of cinchonidine : 
June 24, Blo Bay M; 1:000 gram cinchonidine sulphate. 
CaO 10:35 A. M., Oe2 5007 5° nt oh 
Fe 205 12:35 P. M., 0:°325—S* ye a 
1575 
Rabbit diced at 5:40 vp. M., June 25, in convulsions, 
