449 Chittenden and Cummins— Gas Metabolism. 
discernible action on the excretion of carbonic acid. Further, the 
alkaloid did not noticeably lower the body temperature until toward 
the close of the second day, when the quantity given had reached an 
amount nearly sufficient to produce a fatal result. We have then to 
conclude that antipyrine, at least in therapeutic doses, has no special 
influence on the production or elimination of carbonic acid by the 
rabbit. 
