I goo- 1 . ] 



Observations on Blood Pressure. 



5 minims of dilute H.C.N, (equal to 2j4 minims of Scheele's acid) were 

 injected into the fauces. The respiration almost at once became more 

 ample — although this is not fully brought out in the tracing — but it 

 was not hastened ; and the pulse was raised from 87 to 106. No bad 

 effects followed, and y}4 minutes later the animal was reported as quite 

 normal again. Here then a dose of about i minim of Scheele's acid to 

 seven pounds of body weight increased the amplitude of the respiration, 

 slightly hastened the pulse, but did not otherwise alter the tracing, and 

 no bad effects were produced. 



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Tracing XXXVI. — q/2q, — Effects of small dose of H.C.N. Dose administered just before tracing 

 begins. 4 Respiration very ample, pulse slightly irregular, pressure unaltered. 



Tracing 36 is from a dog of about nine pounds weight which had been 

 given ^ grain of morphia half an hour before the experiment 

 commenced. One minute before the tracing commences 3 minims of 

 dilute H.C.N, were injected hypodermically. A few seconds later (at 4), 

 the respiration was deep and sighing and somewhat irregular, the pulse 

 was slightly faster, and the pressure remained unaltered. After that the 

 respiration became hastened, but beyond the tracing the animal com- 

 pletely recovered. Thus a slightly larger dose than Professor Hobday 

 recommended, about i minim of Scheele's acid to six pounds of body 

 weight, produced no bad effects when given hypodermically. The chief 

 alteration noticed was marked increase in the amplitude of the 



respiration. 



9 8 



Tracing XXXVII.— 3/10.— Effects of H.C.N. Dose administered at S. 9 Breathing very ample, 

 pressure rather higher. 



