226 Transactions of the Canadian Institute. [Vol. VII. 



administered hypodermically. At 20 he was placed horizontal and 

 respiration of a very fast nature at once commenced. In the tracing the 

 big waves represent the pulse, slow because asphyxial, and the little 

 ones are the respiration. The pulse is sixteen per minute, and the 

 respirations are sixty. Beyond this the pulse hastened, the pressure 

 improved and the animal completely recovered. No artificial respira- 

 tion was here employed, and it seems probable that this animal was 

 saved by H.C.N. The placing of him horizontal greatly aided the 

 result. 



21 20 19 18 



Tracing XLIV.— 3/10.— Antidotal use of H.C.N. Animal vertical. 18 Asa result of Chloroform 

 pressure fell and respiration stopped here. 19 Animal apparently dead. H.C.N, hypodermically. 20 

 Horizontal. 21 Respiration 60 per minute, pulse 20 (large waves are pulse and smaller ones respiration). 

 Animal recovered. 



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Tracing XLV. — 3/1 1.— Antidotal use of H.C.N. Animal being vertical, Chloroform pushed, pressure 

 fell and respiration ceased at q, 10 H.C.N, given. 11 Pressure rising, respiration rapid (not shown on 

 tracing). 



In another case an animal was apparently saved from fatal chloro- 

 form poisoning only to die from H.C.N, poisoning. A dose equal to 

 I minim of Scheele's acid to three pounds of body weight was used, 

 and hence it was not to be wondered at that he eventually died. 

 Tracing 45 was taken from this case. While the animal was in the 

 vertical posture chloroform was pushed, and at 9 respiration stopped, 

 and the pulse as usual became exceedingly slow — ten per minute — and 

 the pressure fell to almost zero. At 10, twenty-five seconds after the 

 cessation of respiration, 71^ minims of dilute H.C.N, were injected into 

 the fauces. Respiration of a very rapid nature commenced almost at 

 once, although it produced no sign on the tracing, and at 1 1 the 

 following note was made : " Blood pressure rising ; respiration good 

 although not shown on chart." Thus, so far nothing but good had 

 resulted from the H.C.N., and the animal seemed certain to recover. 

 But now symptoms of H.C.N, poisoning set in as follows : 2i/< minutes 

 from the time of administration of the H.C.N, natural respiration 



