192 



laries, while white globules adhering to the parietes of the 

 vessels arrange themselves in a layer upon this inner surface 

 of the Avails ; and second, in the " wandering out " of these 

 Avhite blood-cells through the stomata, demonstrated by 

 Recklinghausen in the walls of the finer blood-vessels by 

 virtue of that amoeboid movement which is one of the most 

 remarkable attributes of the white blood-corpuscle, and so 

 aptly illustrated by an English commentator on Professor 

 Huxley's lecture upon protoplasm, when he explains the 

 process of an amoeba taking a minute diatom into its substance 

 for food, by comparing it to a lump of dough growing of 

 itself gradually around an apple to make an apple-dumpling: 

 the wliite blood-corpuscles Avhicli have thus Avandered out 

 then constitute Avith exuded serum that yellow fluid, so long 

 knoAvn under the name of pus, and hitherto generally 

 supposed *o be a product of the breaking doAvn of tissue. In 

 sup])ort of this doctrine experiments upon frogs and rabbits 

 paralysed by Avoorara are described in Avhich the mesentery 

 of tlie animal being exposed and spread out upon the field of 

 the microscope, multitudes of Avhito corpuscles Avere seen in 

 all stages of transit from the interior to the exterior of the 

 vascular Avails, in Avhich latter position they constituted 

 ordinary pus-globules. 



Of course such a novelty in medical science has met with 

 numerous assailants, among Avhom the most prominent seems 

 to be Prof. Holman Balogli, of Pesth, Avho, in an article in 

 ' Virchow's Archives' (Erste Heft, Band xlv, S. 19, u. s. av.), 

 asserts that in spite of the most prolonged and careful atten- 

 tion, not once could he see the transit of the Avhite blood- 

 cells through the stomata in the vascular Avails, Avhich he 

 thinks, if they exist, are such minute pores that they can give 

 passage only to fluids. His observations are, hoAvever, sharply 

 commented upon by Dr. A. Schklarevvski, of Moskow, in the 

 folloAving volume of the 'Archives' (Band xlvi, Hft. 1, S. 

 116), and Cohnheim's experiments appear (' Transactions of 

 Pathological Society of London,' vol. xix, p. 467) to haA^e 

 been repeated before the London Pathological Society in 

 April, 1868, by Dr. H. Charlton Bastian, of London, Avith 

 entire success. In our OAvn couTitry, Lieut. -Col. J. J. Wood- 

 ward, Surgeon XF.S. A., stated during a lecture at the Phila- 

 delphia College of Physicians, May olst, 1869, that the 

 experiments of Cohnheim had been tested under his direction 

 in the Surgeon-General's Office at Washington, and that he 

 had found the description of phenomena singularly accurate; 

 the observations on frogs being fully corroborated, as far as 

 fhey had time to repeat them, in every particular, and Dr. 



