252 



no one two years since, when challenged by Cohnheim at 

 the meeting of German physicians and naturalists, could say 

 he had seen. 



3. On the Eelations of Vessels and Nerves to the 

 Process of Inflammation, By S. Stricker. 



4. On Traumatic Encephalitis. By Dr. Friedrich 



Jolly, or Munich. 



5. Researches on the Yelk-cleavage and Blastoderm- 



formation IN the Hen's Egg. By Dr. Josef Oella- 

 cher, of Innsbruck. 



6. On the Endogenous Formation of Pus-corpuscles in 

 the Conjunctiva of the Rabbit. By Dr. L. Oser. 



7. On TkE Inflammatory Changes of Muscular Fibres. 



By Dr. Janovitsch Tschainski, of St. Petersburg. 



8. On the Tissue Changes in the Inflamed Liver. By 



Dr. Andrew V. Huttenbrenner. 



The conclusions at which Holm arrived in his researches 

 upon inflammation of the liver have since been disputed by 

 Koster and You Josef. Holm's description culminated in the 

 positive assertion that on injury the liver-cells became fatty 

 granular cells, which formed circles around the injuring body, 

 and became finally converted into fibres, so that granular cells 

 became granular fibres, Avhich passed into the hepatic cica- 

 trix. Furthermore, Holm taught that at places where the 

 needle which is passed into the liver strikes the cells the in- 

 flammation is more intense than at places where it strikes 

 only connective tissue. Although he afterwards spoke of 

 nuclear disease in the liver-cells, and asserted the fact that 

 the small cells (granulation-cells) were derived from the mul- 

 tinuclcar liver-cells, he still added that he Avas not in a posi- 

 tion to be able to follow out how the young cells could become 

 free. Their appearance, he stated, in more or less compact 

 heaps, as may sometimes be observed, probably fiivoured the 

 above assumption. In assuming their origin from counec- 

 tive-tissue-cells, he could find no more sure holding point. 

 To this last part of Holm's account Koster turned his atten- 

 tion, and this investigator, basing his ideas upon a more 

 recent theory of inflammation, looked upon the pus-cells in 

 the liver as colourless blood-corpuscles. 



The statements of Holm and Koster concerning the forma- 

 tion of pus are, however, nothing more than the echoes of the 

 then prevailing views. At the time of Holm's publication 

 suppuration from parenchymatous cells was the order of the 

 day, whilst at the time of Koster's migrating blood-corpuscles 

 were coming into note. Thus pus was attributed by Holm 



