STUDY OF COCCIDIA MET WITH IN MICE. 277 



A Study of Coccidia met with in Mice. 

 By 



J. Jackson Clarke, M.B.L<oii<1. 



With Plate 30. 



Nearly all that has been published on Coccidia of mice is 

 contained in the writings of Eimer^ and Th. Smith. ^ Ludwig 

 Pfeiffer,^ in reference to what these authors have said on this 

 subject, concludes : '' Unsern friihern Auseinandersetzung 

 nach, handelt es sich hier um das Schwarmercystenstadium 

 einer Coccidie : das dauercystenstadium ist unbekannt." In 

 order to supply data which may fill the gap thus indicated, I 

 venture to submit the following observations. 



A white mouse, kept in a place previously occupied by 

 rabbits, was found dead. Dissection revealed the presence of 

 large numbers of Coccidia in every part of the alimentary 

 tract beyond the cardiac opening of the stomach. There was 

 no other abnormal feature. Sections of the intestine showed 

 an altered condition of the epithelium, but although decom- 

 position had not begun when the tissue was fixed I could not, 

 apart from the encapsuled parasites collected in the lumen of 

 the gut, have been certain that epithelial infection by Sporozoa 

 was present, so soon after death do some of the intracellular 

 protozoa lose their characters. 



The contents of the intestine were spread on a clean slide, 



' Eimer, ' Ueber die Ei- oder Kugelformigen sogenannten Psorospermien, 

 &c.,' Wiirzburg, 1870. 



2 Tb. Smith, Wasbiugton, 'Journal of Comp. Med. and Surg.,' 1889. 

 ' L. Pfeiffer, 'Protozoen als Krankbeitserriger,' 1891, p. 57. 

 VOL. 37, PART 3. — NEW SEB. T 



