292 J. JACKSON CLARKE. 



in which Coccidium oviforme usually presents itself in 

 sections is the spherical granular body represented in fig. 9 to 

 the left. The granules (b) stain slightly with eosin, but remain 

 transparent. They have, no doubt, the same signification as 

 the Gregarina corpuscles^ in the higher Sporozoa, i. e. they 

 serve as stored food. The " dauerform " (L. PfeifFer) of the 

 parasite is represented in the same drawing to the right. In 

 it the granules have disappeared, and the nuclear body (a), 

 which is round in the spherical-granular phase {a'), is oval 

 in the encapsuled parasite. In neither case, however, does 

 the nucleus give the reaction of chromatin, but is stained by 

 the eosin. One other phase of the parasite may be mentioned 

 in passing. This is a small, dense, spherical body, devoid 

 alike of granules and of nuclear body, and staining throughout 

 without eosin. Sometimes a parasite possessing a thick oval 

 capsule is found to have broken up into sickle-shaped swarm- 

 spores, but the rule is that when the parasite multiplies whilst 

 still within the body of the host, it has either no capsule at 

 all or only the delicate so-called primordial capsule. It is to 

 the changes which lead to subdivision of the parasite within 

 the host that I wish to direct attention. R. PfeifFer" first de- 

 scribed swarm-sporing, but chiefly in fresh specimens, and 

 without any detailed account of nuclear processes. L. Pfeiffer 

 (loc. cit., p. 45) described distinct hsematoxylin-stained nuclei 

 in the process of swarm-sporing, and says, " Eingehendere 

 Untersuchungen sind hier noch sehr nothig, dar der mehr 

 oder weniger akute Krankheitsverlauf von Massgebenden 

 einfluss ist auf die Vermehrungsweise des zugehorigen Para- 

 siten." 



Among the parasites in actively extending lesions of the 

 rabbit's liver some present a distinct " geflammte Kern," like 

 that shown in fig. 10 (c). Such nuclei take only the eosin of the 

 stain, or at most a slight tinge of purple at their edge. Most 



> The chemical nature of these bodies is not yet determined. They dissolve 

 n alkalies and mineral acids, and are not fat, nor do they contain lime. See 

 Max Wolters, loc. cit. 



' R. Pfeiffer, ' Beitrage zur Protozoenforschung,* Berlin, 1891. 



