OBSERVATIONS ON YARIOUS SPOEOZOA. 801 



Pig. 12. — Intra-cellular coccidium, the nucleus, c, of which is dividing by 

 regular mitosis, b. Cell-protoplasm with food-granules, a. Host-cell, x 

 1000 diams. 



Fig. 13. — A coccidium which shows, besides the main nucleus, a nuclear 

 spindle, x 1000 diams. 



Fig. 14. — An encapsuled coccidium (capsule, c) with peripheral particles of 

 chromatin, b, which are connected with a central nuclear mass, a, by achro- 

 matic filaments, x 1000 diams. 



Fig. 15. — An epithelial cell, a, of the rabbit's liver filled with nucleated 

 sickle-spores, b. X 1000 diams. 



Fig. 16. — An intra-cellular coccidium with numerous minute chromatin 

 granules at a, the periphery. 



Fig. 17. — An intra-cellular (host-cell, a) coccidium showing close-set peri- 

 pheral rods of chromatin (c) connected with a central nuclear mass (b) by 

 achromatic filaments, x 1000 diams. 



Fig. 18. — A coccidium with peripheral chromatin rods seen in a surface 

 view, and showing the mode of subdivision, x 1000 diams. 



Fig. 19.— Part of the epithelial lining of the rabbit's cystadenoma showing 

 large free parasite with peripheral rods and granules of chromatin, and at 

 X a multinucleated parasite. X 1000 diams. The free parasite is seen in 

 surface view. 



Fig. 20. — a. Granular coccidium with a slightly irregular nuclear spindle. 



b. A parasite with a nucleus similar to that shown in Fig. a, but with 

 granules of chromatin at the left half of the spindle. 



c. Granular coccidium, tiie nucleus of which has become altered so that it 

 presents a collection of granules of chromatin. 



d. Granular coccidium, of which the outer part of the nucleus is separated 

 in an irregular spindle (1), whilst the central part remains unchanged (2). 



e. A similar condition to that shown in Fig. d. 

 f. and g. Irregular mitoses. 



h. A condition similar to that shown in Figs, d and e. The central 

 unaltered part (2) of the nucleus stained with eosin ; the peripheral part (1) 

 (irregular spindle) stained with haematoxylin. 



i. Irregular spindle. 



_;. Elongated nucleus stained densely with hsematoxylin. 



h. Irregular mitosis. Left extremity of the chromatin band stained blue, 

 right extremity crimson. Acid haematoxylin alone. 



/. Irregular mitosis, granules stained purple. 



m. A large parasite in a phase equivalent to that with peripheral arrange- 

 ment of rods, the latter replaced by granules of chromatin. 



n. Large parasite with peripheral rods undergoing segmentation, one of 

 the segments crescent-shaped. Optical section. 



