144 DR. BEALE, ON THE CATTLE PLAGUE. 
Dr. Beale discusses the origin of these masses of germinal 
or living matter, and thinks they may be enlarged white cor- 
puscles; or caused by the adhesion together and subsequent 
growth of other particles, perhaps from the growth of germs 
derived from without; or, lastly, an outgrowth from the 
lining membrane. The congestion is probably due to the 
impediment offered by the increase of material just noticed. 
Dr. Beale notices that inflammatory lymph is not frequently 
met with, and thinks this is due to the fact that the capilla- 
ries become completely obstructed before time has elapsed 
for the outpouring of liquor sanguinis. In inflammation, 
however, the stage of dilatation is more prolonged, and the 
arrest less sudden ; as a consequence of this, the thin walls 
allow the passage of fluid more readily. It would appear, then, 
that the local congestions produced by the increase of germinal 
matter lead in turn to an alteration in the composition of the 
blood and the tissues around. 
2. Changes in the tissues.—A like increase of germinal 
matter is observed in the tissues generally, as well as upon 
the free mucous surfaces, as a consequence of the congestions. 
The papules which project above the level of the skin, in 
Fic. 5.—Fibrous tissue of the corium or true skin from the softened part of 
the papule. The intervals between the fibres are occupied with germinal 
matter, ‘‘ contagium,” growing and multiplying rapidly. ~x 215. 
the seat of the “ eruption,” are due to the increased growth 
of the germinal elements of the derma and the cuticular 
cells, as well as of germinal matter derived from without. 
These minute masses of germinal matter multiply with 
great rapidity, and extend amongst the bundles of the fibrous 
tissue, making their way, in part, to the surface, in fact, 
separating the bundles of the areolar structure, and even 
causing thin atrophy. The fibres soon become replaced by 
