DR. BEALE, ON THE CATTLE PLAGUE. 145 
“an amorphous mass of minute masses of germinal matter, 
varying much in form and products resulting from the decay 
of some of these particles.” 
The connective-tissue-corpuscles increase in size. These 
changes are well seen in Fig. 6, contrasted with the healthy 
state shown in Fig. 7. 
Fic. 6.— Enlarged connective-tissue- Fic. 7.—Connective-tissue-corpuscles. 
corpuscles. Surface of mucous mem- Surface of healthy mucous mem- 
brane over epiglottis—cattle plague brane over epiglottis, just beneath 
just beneath the epithelium. 700. the epithelium. x 700. 
The same increase is found in the cuticle, especially about 
the middle layers, the true epithelial cells being invaded and 
often replaced by the nuclear bodies, which invade from the 
exterior, as seen in fig. 8, so that there are two processes taking 
place at the same time, both, however, consisting of the 
growth of germinal matter; but the germinal matter is of 
two kinds—1, that belonging to the normal tissues, which 
ows in consequence of being supplied with an increased 
amount of pabulum; and_ 2, particles of germinal matter 
which have invaded the tissues from the blood. The last 
are alone considered to be contagious. These are seen in 
fig. 8, in the outer part of the cuticular cells. 
Fic. 8.—Cuticular cells under scab. Eruption on mamma, showing 
how the cells are invaded by the growth and multiplication of the 
minute particles of germinal matter (contagium?). x 700. 
