236 DR. MOXON, ON MOTOR NERVE. 
His account is fully verified by Dr. Richard Greef, in Max 
Schulze’s new journal (Bd. i). 
In 1840 Quatrefages saw Doyere’s cone in Holidina para- 
doxa, and other observers in other animals, especially nema- 
toid worms; all agree in describing the conical ending of the 
one fibre on the other, but the muscle was in all cases of 
the unstriped kind, and the nervous nature of the fibre which 
joined it could not be proved. The muscles of Tardigrada, in 
which the observation is most satisfactory, are unstriped and 
without sarcolemma. 
In 1846 Wagner made a doubtful statement as to the 
ending of a nerve by piercing a muscle. 
In 1858 Munk spoke of nerve-fibres in frogs disappearing 
like stumps broken off. 
In 1860 Kihne, and Margo six months after him, described 
the ending of nerves by piercing the sarcolemma of trans- 
versely striated muscle, and since that time several other 
observers, especially Rouget, Krause, and Cohnheim, have 
given similar descriptions, differing in points of minute 
detail. 
In 1860 Dr. Beale gave a description of an essentially 
different mode of nerve termination, in which he was sup- 
ported by Kolliker, Rouget, and Krause; but the latter two 
observers have since described the nerves as ending directly 
upon the muscle-fibres. Dr. Beale has since, so lately as 
1864, reaffirmed the same view, describing the nerves as con- 
tinuous, with a nucleated meshwork outside the sarcolemma. 
Although it is now late to appear with such a claim, yet it 
is quite true that the accompanying observation was made in 
the spring of 1862,* and was entirely independent of any 
other observations. Indeed, it was only recently, in reading 
the subject for the purpose of this paper, that I became aware 
of the existence of descriptions of direct union of nerve with 
muscle. The books used by English students do not allude 
to such a mode of termination. 
When investigation is made upon groups of muscle-fibres 
there are many obvious sources of fallacy which are avoided 
by using an instance such as that I now offer, wherein the 
muscle-fibre is single, and is supplied by a single nerve-fibre. 
Again, in scrutinising with the high powers necessary for 
these observations the muscles of vertebrata we are apt to 
be misled by the corpuscles of connective tissue found in the 
course of nerves and vessels in all animals of that sub-kingdom. 
On the other hand, I believe I may say that no true connec- 
* The drawing was shown to Dr. Braxton Hicks in 1863. 
