146 QUARTERLY CHRONICLE. 
This at once strives, by imbibition, to assume the globular 
shape. The remaining portion may or may not ultimately 
undergo similar transformation. Inflamed serous membranes 
become often densely “‘nucleated.”’ In the deeper layers, the 
“nuclei” are very elongated. At the surface they are per- 
fectly globular, and are detached as minute opaque balls. 
These balls are the granulation- or the pus-corpuscles. On 
imbibition, one portion of their soft material swells out, en- 
compassing the rest, which, when forming a single uniform 
globule, goes under the name of granulation-corpuscle—when, 
on the other hand, broken up into. several granules, consti- 
tutes the famous pus-“ cell.”” This is an example of a second 
mode of “cell”’-formation. Here the secondary globule is 
shaped from a portion of the primary mass. In some instances 
these “ nuclei” or balls will, when still enclosed within the 
surrounding texture, undergo the above-mentioned change 
on imbibition ; and thus whole rows of granulation- or pus- 
corpuscles are seen to form. This second mode of “cell”’- 
formation is still more strikingly manifested in epithelial 
textures. In the mucous membrane of the nose, for instance, 
the faint oval “nuclei” of the large scales become during 
disintegration more and more distinct and globular. The 
surrounding material of the scale gradually liquefies, and the 
minute balls, thus liberated, expand by imbibition into 
mucus- or pus-corpuscles. It often succeeds in causing them 
to form in all perfection whilst they are still contained within 
the scale. In abscesses of the skin the pus-corpuscles are 
formed in exactly the same manner. They can often be 
watched, fully shaped, still enclosed within the scale. Here, 
it would seem, are “ cells’ not the result of life, but rather 
of death. The multiple ‘ nuclei” of pus-corpuscles are not 
the result of over-fecundity, but are simply due to the dis- 
integration of the non-imbibing portion of those oval or 
spherical sharply defined bodies which are themselves so well 
known under the name of “nuclei.” The disintegration of 
this non-imbibing portion can be traced through all possible 
stages, down to the cluster of most irregularly shaped granules 
(which, notwithstanding, have been looked upon as the result 
of fissiparous division), and has been made to represent the 
crowning feature of the cell theory. The same minute balls 
found swimming in the serum of a blister were seen, when 
treated with water, to disclose single bright sharply defined 
“nuclei; when treated with acetic acid, to reveal the most 
typical multiple nuclei of pus-cells. 
II. Experimental Verification.—In all the above-cited ob- 
servations the existence of a viscid imbibing material was 
