STRUCTURE OF THE MAMMALIAN GASTRIC GLANDS. 373 



rarely presents peculiar sheaf-like and concentric forms 

 which are not unlike the figures published by Macallum/ 

 Mouret/ and others, of the nebenkerne in the pancreatic cells 

 of Batrachia. 



A coarse fibrillation, similar to that exhibited by the outer 

 protoplasmic zone of the chief cell, I have also observed in 

 the cells of the oesophageal glands of the frog, and in the 

 serous glands of the gustatory region of the tongue of the 

 rabbit and dog, the fibrillse being strongly chromophile and 

 iron-holding in each case. Solger ^ has described in the serous 

 cells of the human submaxillary gland, and Erik Miiller '^ in 

 the submaxillary glands of the guinea-pig, rod-shaped elements, 

 placed vertically in the bases of the cells, which stain intensely 

 in haematoxyliu. It appears probable that these also are small 

 masses of protoplasm which owe their affinity for hsematoxylin 

 to the fact that they are strongly impregnated with prozymogen. 



Between the coarse fibrils in the base of the cell may be 

 seen small vacuoles containing fluid, and in the pepsin-secret- 

 ing cells of the stomachs of Batrachia the outer zone appears 

 rather vacuolated than regularly fibrillated. In osmic acid 

 specimens minute fat droplets may usually be seen in the outer 

 ends of the cells, the border granules of Langley. 



The nucleus of the chief cell of the body of the fundus gland 

 is placed near the base of the cell in the resting condition. 

 It is spherical or slightly oval in shape, frequently exhibiting 

 slight irregularities of contour. A well-defined chromatin 

 network and one or two large oxyphile nucleoli may be made 

 out in all stages of secretion. The latter are always invested 

 by a thin layer of basic chromatin, which frequently collects 

 in small masses at certain points on the periphery of the 

 nucleolus, as has occasionally been observed in the nuclei of 

 nerve-cells. 



It will be seen from the foregoing that there are two salient 



' 'Trans. Canadian Institute/ vol. i, part ii, 1891. 



' Op. cit. 



' ' Anat. Anzeiger/ Bd. xi. 



* ' Arch. f. mik. Anat.,' Bd. xlv. 



