382 R. R. BENSLKY. 



The cells of the pyloric glands contain neither in the fresh 

 condition nor in the hardened and stained gland granules 

 of zymogen. Furthermore, the protoplasm of these cells is 

 not chromophilous to nuclear dyes^ and examination for masked 

 iron by the methods already indicated reveals hut a trace of 

 prozymogen. The cells of the transitional portion of the 

 gland resemble most closely those of the surface, hut contain 

 a relatively larger amount of protoplasm. By means of Mayer's 

 muchaematein it may be shown that these cells always contain 

 a small mass of mucus at their free ends, but this is so small 

 that, when using less decisive staining methods, it is readily 

 overlooked, and the cell regarded as entirely protoplasmic. In 

 these cells mitoses are fairly numerous, although they also 

 occur in all parts of the gland proper. 



These pyloric glands present exactly the same features as 

 the neck and duct of the fundus gland, — that is, although 

 the true pyloric gland cells differ both in general appear- 

 ance and in structure from the cells of the surface, in 

 passing from one to the other along the gland at no point 

 can one discover an abrupt change from one type of cell to 

 the other. 



The secretion phases in the pyloric glands of the cat are 

 peculiar, and are represented in figs, 8 — 10. Fig. 8 shows 

 the condition of the gland after a fast of twenty-four hours' 

 duration. The cells are comparatively long, with a spherical or 

 oval nucleus placed near the base of the cell. The stored-up 

 secretion is found, for tlie most part, in the form of a narrow 

 zone along the lumen of tiie gland, although it is not uncommon 

 to find a second mass of secretion in the deeper portion of the 

 cell near the nucleus (fig. 8, a). It is also quite common to 

 find this second mass of secretion more stainable in indulin 

 than that along the free border, the cell then presenting an 

 appearance closely resembling that already described for the 

 cells of the lowest portions of the duct of the fundus glands. 

 Sometimes, as in the neck of the fundus glands, the mucin is 

 precipitated in the form of irregular flakes or granules. A pro- 

 longation of the fasting period even to four days does not 



