144 MRS, ERNEST HART. 
measured by a millimeter rule. The resulting numbers 
give the diameters of the corpuscles in micro-millimeters. 
Of course the mean of a great number of measurements 
must be taken. I generally take the mean of fifty measure- 
ments. The area in yp” is obtained by the well known 
formula of mr’. 
To take an example: 
Let 7°60 = the diameter of a normal corpuscle ; 
and 3°8u = the radius: then 
mr? = 7. 14:44u? = 45°36p?. 
45. 36? is therefore the area of a normal human corpuscle. 
To obtain the unit of corpuscular richness, 7. e. the amount 
of hemoglobin in a volume of ry”, the amount of hemo- 
globin per corpuscle must be divided by the area. 
In the following table, which I have prepared, these cal- 
culations, and others to which reference has been made 
above, have been worked out. The number of corpuscles in 
a cubic millimeter is taken as invariable in the examples of 
normal and anemic blood (this is not infrequently the case) ; 
all the other figures vary, however, from the normal in dif- 
ferent degrees, the unit of corpuscular richness being finally 
the only figure that gives the exact ratio between the normal 
and pathological states. 
ee e. Ae (~h 2 ad 
oO og o = 
= A oie ie ae Bs 
ae a2 a : ioe 
oe ~ I © Sp = Cy ue 
= = o = i = oSs 
os oj ag of a ° £22 
no BS 2 ns o mn s 0° 
Bn 3 ° 23 3 ed Pr. | 
es | s3|s2| BS |o| & |S58 
On 2 2s ou ° ° S52 
Ss Ou om oso H =) ee 
g aS — by as Ss 
Se on 50 ealss 3 oH oCn 
od I S Cs Ss °o Ba 
x S os 
S = 8 én s 2 & = 
Z es ss ZH ra) 4 | 
Wh, er. Z 
ar. | wy. gr Me M2 | up gr 
The corpuscles in a nor- 
mal state of health . |4,500,000) 0°134, 29°77/33,580,000) 7°60) 45:36 0°66 
Slight anemia, with di- 
minution of the size 
of the corpuscle - 4,500,000 0°082 18°66 54,878,048 6°50) 33-18 0-56 
Marked anemia, with 
increase of the size of 
the corpuscle . - |4,500,000 0°062 13°77'72,580,645' 8-20 52-81 0°26 
Pathologically these exact or minute analyses are most 
interesting, though their outcome clinically and therapeuti- 
