62 QUARTERLY CHRONICLE. 
rior and lateral. Sometimes the lesion was in the form of a 
granular deposit around blood-vessels; sometimes in the 
form of globular masses or rings, arising from injury and 
displacement of the white substance of the adjacent nerve- 
fibres. The latter appearance was more frequent in the 
white columns and along the sides of fissures containing 
blood-vessels, where the tissue had occasionally the aspect 
of a moth-eaten cloth. In some places the lesional spots 
were exceedingly small, and might easily have been mistaken 
by an unpractised eye for the natural appearance of the 
art. 
Although I shall abstain from giving any decided opinion 
on the exact nature of the morbid action in tetanus until I 
have examined more cases, the plan of treatment which I 
should try would be the following :—Division of the wounded 
nerve as early and as high up as possible ; cupping along the 
course of the spine; frequent doses of calomel combined with 
opium; and potassio-tartrate of antimony, repeated, during 
the severer paroxysms, at short intervals and in sufficient 
quantity to produce nausea, or perhaps vomiting. The 
chief object of the tartrate of antimony is to subdue the 
spasms, but it might also assist in arresting the morbid 
action of the blood-vessels. Some years back, in the columns 
of this journal, I recommended the use of tartrate of anti- 
mony in those violent and prolonged paroxysms of hysteria 
which are so intractable and distressing, and I have never 
known it fail. As soon as nausea supervenes, the spasms, 
however violent, begin to relax; and if the paroxysm be 
excited or prolonged by the presence of undigested food in 
the stomach, the vomiting will prevent its recurrence. In 
tetanus, any depression that might be caused by the antimony 
would be much less than the exhaustion of the nervous 
system resulting from the violence of the spasms. 
I shall be glad to receive the spinal cords and medulle 
oblongate of any patients that may die of tetanus. If they 
cannot reach me immediately, they may be cleanly cut with 
a sharp knife into pieces about an inch long, and preserved 
in a solution of chromic acid, in the proportion of 1 part to 
300 parts of water. I shall also be glad to receive cords 
belonging to cases of muscular atrophy or “ wasting palsy.” 
[We have given the above cases from the ‘ Lancet,’ to 
show our medical readers what may yet be expected from 
microscopic research with regard to nervous diseases. It 
is not because, by a rude inspection with the naked eye, no 
changes can be observed in nervous structures where nervous 
