88 PROCEEDINGS OF SOCIETIES. 
That when extract of opium is taken up with rectified 
spirit 56° O.P., and evaporated again to an extract, crystal- 
lization does not take place, or only to a very trifling extent. 
That morphine and its salts, and perhaps other opium prin- 
ciples, do not crystallize readily from their solution in wine. 
Finally, it remains for us to express our obligation to our 
friends Mr. Morson, of London, and Messrs. T. and H. Smith, 
of London and Edinburgh, for the courteous way in which they 
have assisted us with specimens, when working upon those of the 
alkaloids which exist only in minute quantities in opium; without 
this assistance we could scarcely have procured them in a state 
of reliable purity. —Pharmaceutical Journal, 1864. 
Royat Socrirry, May, 18, 1864. 
New Oxpservations wpon the Minute Anatomy of the ParILum 
of the Froa’s Tonauxn. By LioneS. Beare, M.B., F.R.S., &e., 
Fellow of the Royal College of Physicians, Professor of 
Physiology and of General and Morbid Anatomy in King’s 
College, Physician to King’s College Hospital, and Honorary 
Fellow of King’s College, London. 
( Abstract.) 
AFTER alluding to the observations of Axel Key, whose results 
accord with his own more closely than those of any other observer, 
the author refers particularly to the drawings of Hartmann, the 
latest writer upon the structure of the papille. According to the 
author, Dr. Hartmann, owing to the defective method of prepara- 
tion he employed, has failed to observe points which had been seen | 
by others who had written before him, and which may now be 
most positively demonstrated. Hartmann’s process consisted in 
soaking the tissue for three days in solution of bichromate of 
potash, and afterwards adding solution of caustic soda. It can be 
shown by experiment that many structures which can be most 
clearly demonstrated by other modes of investigation, are rendered 
quite invisible by this process. Hartmann’s observations, like those 
of the author, have been made upon the papille of the tongue of 
the little green tree-frog (Hyla arborea). 
With reference to the termination of the nerves in the fungiform 
papille of the tongue of the Hyla, the author describes a plexus of 
very fine nerve-fibres, with nuclei, which has not been demonstrated 
before. Fibres resulting from the division of the dark-bordered 
fibres in the axis of the papille can be traced directly into this 
plexus. From its upper part fine fibres, which interlace with one 
another in the most intricate manner, forming a layer which 
appears perfectly granular, except under a power of 1000 or 
higher, may be traced into the hemispheroidal mass of epithelium- 
