46 



DR. KLEIN. 



ill the outer layers. Sometimes in the whole length of the 

 bulb, within an external sheath of spindle-like cells, we 

 recognise small compactly crowded young cells only. I have 

 also seen some sacculi in which the hair-shaped body was 

 wanting. These, however, were oval, and did not by any 

 means present the appearance of cysts, as described by 

 Remak ; others I have seen in Avhich this body was double. 

 There occur also sacculi in which no distinct lamellation is 

 ])resent. In these cases the sacculus presents only a thick 

 wall consisting of a connective- tissue matrix, in which 

 spindle-looking cells may be observed. Finally, there are 

 hair-shaped bodies with but one extremity imbedded in a 

 sacculus raised free above the surface. 



The sacculus is covered with an endothelium, which is 

 unusually thick and large, and clearly granular ; the cells 

 possess either a simple clear nucleus, with a distinct nucleo- 

 lus, or the nucleus is in the act of dividing or is double. In 

 short, we have before us a condition which we ought to 

 designate a morbid^ change of the endothelium. The endothe- 

 lium supports on some sacculi, for the greater part of the 

 surface, delicate cilia. With the structures described there 

 are connected larger and smaller bud-shaped knots, on which 

 either ciliated endothelium only is to be observed, or this covers 

 a transparent matrix, in which are contained, more or less 

 abundantly, young cells ; or else the knot consists only of 

 young cells covered with ciliated endothelitim. In fresh pre- 

 parations, mounted in serum, the movement of the cilia is 

 exceedingly lively; but on other extensive portions of the 

 surface of the membrane a similar ciliated endothelium may 

 be discovered, as well as knots similar to those just de- 

 scribed. The signification of these knots, and the history of 

 their development, as well as that of the hair-shaped struc- 

 tures, we pass over here, as this does not belong to the plan 

 of this communication. This much only we shall remark, 

 that the sacculi of the hair-shaped bodies have nothing to 

 do with cysts in a common sense, but, as will be shown in 

 another place, stand in closer relation with chronic inflamma- 

 tion, having their complete analogies in certain chronic in- 

 flammations in mammals. 



If we examine a fresh preparation of this kind with a No. 7 

 or 8 Hartnack, and survey more minutely the cellular elements 

 which occur in the tissue of the sacculus, or in one of the 

 knots described, or also in the tissue of the membrane, we 

 shall discover some element or other in Avhich is to be seen 

 a clear circular spot, like a cavity filled Avith fluid. The cell 

 presents nothing striking in size, its nucleus is situated 



