362 TIMOTHY EICHARDS LEWIS. 



lateral prolongations of the protoplasm, and how much to the 

 aspect which would be presented when this ribbon-like form 

 undergoes rapid spiral contractions. In the above figures an 

 attempt has been made to reproduce the most striking of these 

 dififerent appearances, and a couple of red blood-corpuscles have 

 been introduced to indicate the relative size under the same 

 magnifying power. 



At 5 p.m. the organisms manifested signs of losing vitality, 

 became more ribbon-like and pointed — almost, if not quite, 

 ' lashed,^ at the thicker end also ; moreover, a clear space is 

 observed at a distance of from 2 to 3 /t^ from the point highly- 

 suggestive of a vacuole. This is indicated in two or three of 

 the figures. They averaged about 30 fx in length and from 

 1 to 2 ft in width at the thickest part. 



At 8 p.m. only two specimens could be detected in the slide, 

 one quite motionless, the other nearly so. One of these is 

 carefully sketched at a in the engraving ; a vacuole-like spot 

 is observable at one part, and the parasite is granular almost 

 along its entire length. Near this specimen a curved proto- 

 plasmic object was observed to alter its form very slowly, as 

 shown at a, h, c. Its further changes could not be followed, 

 as it was lost whilst its form was being outlined, but I have on 

 two or three occasions observed objects of this character asso- 

 ciated with these parasites, and sometimes think that they 

 must represent either an earlier or a later stage of them than 

 is ordinarily seen. 



Further specimens of blood were obtained from the puppy 

 on the 29th and 30th of October, but no organisms could be 

 detected ; on the 3rd November, however, it is noted that the 

 organisms were very numerous in the blood, and that " the dog 

 looks remarkably well.'^ 



Shortly afterwards the puppy was taken to Calcutta, and 

 when examined on the 25th November no organisms could be 

 detected in its blood. On the 3rd December, however, they 

 were readily found. A specimen which was observed on this 

 occasion may serve to illustrate a phenomenon which I have 

 frequently observed in connection with like organisms in the 



