682 PROFESSOR DR. E. BINZ. 



Protoplasmic Movement and Quinine. 



By 



Prof. ]>r. E. Binz, 



ia Bonu. 



In No. xcv of this Journal, July, 1884, p. 396, the following 

 sentence occurs in the translation of the treatise of Professor 

 Engelmann in Utrecht from L. Hermann's ' Handbook of 

 Physiology :' 



"Binz^ and others have observed that quinine exercises a 

 strongly destructive action on many kinds of protoplasm and 

 on colourless blood-corpuscles. On the other hand, I have 

 given frogs such large doses of quinine sulphate by subcu- 

 taneous injection as to kill them, and have observed the lymph- 

 corpuscles after some hours in active movement.'^ 



My pupil, C. Scharrenbroich, now physician in Pallanza, has 

 already published a reply to this statement of Engelmann.^ 

 He has shown that the discordant statement of Engelmann 

 rests on two reasons : on a diflFerent manner of making the 

 experiment I describe, and on a false interpretation of the 

 stunted movements which Engelmann still saw in the colourless 

 blood-corpuscles of his frogs. Professor Engelmann was good 

 enough soon afterwards to write me as follows : 



* C. Binz, " Ueber die Eiuwirkung des Chiniu auf Protoplasmabeweguug," 

 'Arch. f. mikrosk. Anat.,' iii, p. 383, 1867. 



^ "Einiges Alte iiber Chinin," 'Arch. f. Pathol, u. Pharroakol.,' xii, p. 33, 

 1879. 



