PROTOPLASMIC MOVEMENT AND QUININE. 683 



" Utrecht, June list, 1880. 



'' Dear Colleague^ — Allow me to add a few words to the 

 dissertation of my pupil, C. ten Bosch, on Chinamiue, which 

 I sent to you to-day. As you will see from the work, in case 

 the Dutch does not prevent you from reading it, I have made 

 comparative researches with C. ten Bosch on the action of 

 Chinamine and Quinine on elementary organisms, especially 

 on white blood-corpuscles, and have thereby had opportunity 

 to confirm your important results as to the extremely in- 

 tense action of quinine on contractile blood-cells, also to 

 verify the superiority of this body to Chinamine, which in other 

 respects far exceeds the action of Quinine. 



" I am glad thus to clear away a little mistake which I 

 have caused through my over-sceptical remarks in L. Her- 

 mann's 'Handbook' (art., "Protoplasmic Movement ''). If 

 I can render you a service thereby I will gladly publish a 

 notice as to the settlement of this difference anywhere you 

 think suitable, perhaps in continuation of Dr. Scharrenbroich's 

 article. 



" Of course the remarks as to Quinine will be altered in a 

 possible second edition of the first volume of Hermann's 

 ' Handbook.' The fact on which my sceptical remarks rest is 

 beyond doubt, but it cannot form the basis of an objection to 

 your statements. I am, &c., yours, 



"Th.'w. Engelmann." 

 " To Prof. Dr. Binz, Bonn." 



It appears to me that the matter is thus settled. But should 

 anyone wish for further confirmation of what I have published 

 on the influence of quinine on protoplasm in the above quoted 

 and in later papers, I would refer to the following : 



(1) G. Kerner, ^ Arch. f. d. ges. Physiologic,' iii, p. 136, 

 tab. ii, V, p. 27; vii, p. 135, 1870—1873. 



(2) Buchanan Baxter, ' The Practitioner,' a journal for 

 therapeutics and public healthy London, xi, p. 32-1, 1873. 



