The Termination of Nerves in the Liver. 



By 



A* B. Hacallum, B.A., 



Fellow of University College, Toronto, Canada. 



With Plate XXXIII, figs. 1 to 6. 



After the completion of my studies on the termination of 

 nerves in the cutaneous epithelium of the tadpole, I began 

 investigations on the distribution and arrangement of nerves in 

 other organs, and have now arrived at what I consider important 

 results, more especially in the case of liver. That of man was 

 first employed at the outset of the investigation, but I soon 

 perceived that on account of the small size of the cells here I 

 would have to resort to some other Vertebrate for control pur- 

 poses ; not that the liver of man does not yield definite results, 

 but that these might always be open to doubt if taken alone. 

 Fortunately at that time there were a number of Necturi in 

 the Laboratory Aquarium, and to these I resorted, on the advice 

 of Professor Wright, obtaining from them my most valuable 

 preparations of the liver. The hepatic cells in these are from 

 two to four times in diameter those in man. It is obvious, 

 therefore, that for ascertaining the relations of nerves to the 

 hepatic cells the liver of Nee turns ( = Menobranchus) is the 

 most favorable that can be at the disposal of any histologist. 



I made preparations also from the livers of the dog, rabbit, 

 and frog, which turned out to be of but indiff'erent value, and 

 recognising that the narrower the field of investigation is the 

 more could attention be bestowed on the necessary details of 

 technical manipulation and of observation, I devoted nearly the 

 whole of my time to winning successful results from the livers 



VOL. XXVII, PART 4 NEW SER. I I 



