66 A. B. MACCALLUM. 
terminal sub-epithelial network of Klein and Leboucq. This 
network, as I find it, rests directly on the corium, and its 
meshes are very often as narrow as those described by Klein. 
The excessively fine fibrils forming them anastomose with each 
other, and at points along their course can be seen large 
numbers of delicate swellings, which serve as points of origin 
for intra-epithelial nerve-fibrils. These may terminate directly 
either within or between the cells, or they may branch more 
than once, the delicate twigs resulting in this way terminating 
differently also. 
All intra-epithelial nerve-fibres do not originate from this 
sub-epithelial network. In preparations where the gold has 
not coloured the epithelium too strongly, one can see in the 
fundamental plexus a certain number of fibres, each with a 
series of regularly-placed swellings which give origin to single 
fibrils passing through the corium and ending without branching 
between the cells of either the basal or first intermediate 
layer of the epithelium. These fibrils and their compara- | 
tively large, swollen, beadlike terminations, can be easily seen 
with a low-power objective, such as Hartnack’s No. 4, and have 
been already referred to by me, when describing sections pre- 
pared with nigrosine and saffranine. The terminal beads are 
from three to five times the size of one of the intercellular 
terminations of fibrils of the sub-epithelial network. They are 
best shown in preparations were the gold treatment has been 
only partially successful and where the other terminations are 
not seen. 
Mitrophanow has evidently seen these as well as the ordinary 
intercellular nerve terminations, and he confuses the two kinds. 
In the woodcut accompanying his work, he indicates the 
terminal fibrils as passing directly from the fundamental 
plexus through the corium and terminating in large beads 
between the epithelial cells. In his figs. 1 and 2, he repre- 
sents the same kind of fibrils but he has not given them termi- 
nations as large as I find them to have. He observed no 
sub-epithelial network, but from his fig. 3 he appears to have 
seen the intercellular terminations of fibrils arising out of it. 
