84, HERBERT E. DURHAM. 
It is usual for each mass to be multinuclear—that is, there 
are several foci in close approximation. 
Whether or no the cells of the neighbouring trachea and 
connective tissue take a share in the capsule is not of so much 
interest as it is in the inflammatory processes of Vertebrates, 
because there is no formation of definite fibrous tissue, so far 
as I have been able to observe. It is possible that some 
assistance may be afforded by the connective tissues in the 
neighbourhood ; but anyhow all stages can be seen between 
the rounded leucocyte with its spheroidal nucleus and the 
thinned-out cell with its altered nucleus (cf. fig. 1). 
By such a process of encapsulation the particles are removed 
from the circulation, and thus prevented from causing injury 
or irritation to the tissues with which they might come in 
contact. 
In Section 111 this aspect of the matter will be more fully 
dealt with. 
II. On DiarEepEsis oF LEUCOCYTES CONTAINING PRODUCTS 
oF NorMAL METABOLISM. 
In the above-cited paper (No. 26) I also called attention to 
the emigration of ameboid cells from the body of individuals 
of Asterias rubens; which ameeboid corpuscles contained 
refringent spheres, and were called spheruliferous corpuscles, 
and led to the formation, with assistance of mucous secretions, 
of a brownish slime on the surface of the animal: this slime 
was found to contain such corpuscles in various stages of dis- 
integration (26, pl. ii, fig. 4). 
Vogt and Jung, in describing the dermal branchie of 
Astropecten aurantiacus, say, “Auf dem Gipfel des 
Rohrchens [=branchia] fliessen die Zellenreihe zu einer Art 
Haube zusammen. Aber auf allen Schnitten haben wir stets 
in der Spitze des Réhrchens einen rundlichen Propf von 
kleinen Zellen gesehen die sich nicht wie die andren Gewebe 
farbten und eine gelbe Farbe und wachsartiges Aussehen 
hatten. Diese Propfe kénnten von der Coagulation der in 
