194 W. WALDEYER. 
only in the form of numerous granules during division. Boveri 
is of opinion that the cells with distinct mitosis are the ancestors 
(“ Anlage”’) of the genital cells. 
As a set off to these observations of direct division we have 
very numerous and constantly increasing observations on the 
mitotic process of division. 
For normal karyokinesis the well-known works of Stras- 
burger (190, 191, 193) and Flemming (58—-60) -supply the 
greatest number of examples. In addition to the numerous 
cases there enumerated, I must mention amongst the recent 
literature the following :—Karyokinesis during the growth and 
regeneration of smooth-muscle fibre (Pfitzner and H. 
Stilling in ‘ Archiv f. mikr. Anat.,’ Bd. xxviii, p. 396), Cattani 
(‘ Gazzetta degli ospitali,” 1885), Paladino (‘ Riforma medica,’ 
1886), Busachi (‘ Estratto giornale della R. Acad. di Medic. di 
Torino, 1886, Nos.3 and 4). Karoykinesisin striated muscu- 
lar fibre (Nikolaides, ‘ Arch. fiir Anat. und Physiol,’ Physiol. 
Abtheil., herausgeg. van E. du Bois-Reymond, 1888, p. 441). 
In tooth-forming tissue (Canalis, ‘ Anatom. Anzeiger,’ 1886, 
No. 7). In liver-cells (Podwyssotzki, in Zeigler and Man- 
werck, ‘ Beitriige zur path. Anat. und Physiol., Bd. i, and 
Canalis, ‘ International Monatsber. f. Anat. und Histol.,’ Bd. 
ili, p. 205). As in the animal kingdom, so in the vegetable 
kingdom, every embryological and histological memoir brings 
forward new instances of mitosis. 
In pathological cell-multiplication, also, the mitotic form 
comes into the foreground. Especially J. Arnold, in his work 
on the process of division in marrow-cells (Virchow’s ‘ Archiv,’ 
Bd. xevii, 1884), gives an excellent list of the memoirs dealing 
with the process which have hitherto been published. We 
find this considerably increased in one of the later publications 
of the same author (“Ueber Theilungsvorginge an dem 
Wanderzellen ihre progressiven und regressiven Metamor- 
phosen,” ‘ Arch. f. mikr. Anat.,’ Bd. xxx, p. 205, 1887), and 
continued up till to-day in Schottliinder’s work (181a) from 
J. Arnold’s laboratory. Again, Unna (‘Neuere Arbeiten 
iiber Kern- und Zelltheilung,” ‘ Monatsber. fiir prakt. Derma- 
