504: ARMAND RUFFER. 
EXPLANATION OF PLATE XXXII, 
Illustrating Mr. Armand Ruffer’s paper ‘‘ On the Phagocytes 
of the Alimentary Canal.” 
For particulars see text. 
Fics. 1—7 represent the stages in the development of a macrophage. 
(Zeiss, 3 + +5.) 
Fig. 1. Lymphocyte. The nucleus is somewhat paler and more reticu- 
lated than other mononucleated cells. (Zeiss, id.) 
Fig. 2. Lymphocyte, with a slightly larger nucleus. (Zeiss, id.) 
Fig. 3. The nucleus is increased in size and contains several nucleoli. 
The amount of protoplasm is also larger. (Zeiss, id.) 
Fig. 4. Shows some increase in the amount of protoplasm. (Zeiss, id.) 
Fig. 5. Nucleus and protoplasm are both much larger. (Zeiss, id.) 
Fig. 6. Smaller macrophage. (Zeiss, id.) 
Fig. 7. Macrophage irregular in shape. a. Nucleus with well-marked 
nucleolus (2), and intranuclear network. c. Protoplasm. (Zeiss, 
Ae) 
Fic. 8.—Macrophage. a, 8, y. Healthy bacilli. 6. Partially digested 
bacillus. (Zeiss, 4 + =.) 
Fig. 8 dis.—Macrophage containing bacilli. (Zeiss, id.) 
Fic. 9.—Macrophage containing a partially digested macrophage (a), which 
had taken into its interior and digested a bacillus (a). (Zeiss, id.) 
Fie. 10.—Macrophage. a, d. Partially digested leucocytes. 4, c, e. Frag- 
ments of partially digested nuclei. 4, c. are surrounded by vacuoles. a. 
Partially digested micro-organism. (Zeiss, id.) 
i ie. 11.—Macrophage, containing :—a, 4, e, f Nuclei in more or less 
advanced stages of degeneration.  ¢, d, yg. Partially digested leucocytes. 
(Zeiss, id.) 
Fie. 12.—Macrophage, containing:—a, 6, ce, d, e. Leucocytes in various 
stages of intracellular destruction. Nucleus of digested macrophage ? 
(Zeiss, id.) 
Fie. 13.—Macrophage, containing :—a. Partially digested leucocytes, sur- 
rounded by a vacuole. ‘Two healthy bacilli are found in its interior. 4, Di- 
gested microphage with degenerated bacillus (a).  ¢, d, e. Remnants of 
digested leucocytes. Partially digested nucleus (macrophage ?). (Zeiss, 
3 + qs)- 
